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Details on Person MITF-M binds the promoters of v-ATPase target genes

Class:IdReaction:9858883
_displayNameMITF-M binds the promoters of v-ATPase target genes
_doReleaseTRUE
_timestamp2024-11-08 15:55:58
authored[InstanceEdit:9856650] Rothfels, Karen, 2023-12-21
compartment[Compartment:7660] nucleoplasm
created[InstanceEdit:9858881] Rothfels, Karen, 2024-01-14
edited[InstanceEdit:9856650] Rothfels, Karen, 2023-12-21
input[CandidateSet:9858891] MITF-M dependent v-ATPase target genes [nucleoplasm] [Homo sapiens]
[Complex:9825710] MITF-M dimer [nucleoplasm] [Homo sapiens]
internalReviewed[InstanceEdit:9859271] Orlic-Milacic, Marija, 2024-01-17
isChimericFALSE
literatureReference[LiteratureReference:9859469] The H+-ATPase (V-ATPase): from proton pump to signaling complex in health and disease
[LiteratureReference:9859455] Mutations in the X-linked ATP6AP2 cause a glycosylation disorder with autophagic defects
[LiteratureReference:9859449] Mapping the H(+) (V)-ATPase interactome: identification of proteins involved in trafficking, folding, assembly and phosphorylation
[LiteratureReference:9857261] Mitf is a master regulator of the v-ATPase, forming a control module for cellular homeostasis with v-ATPase and TORC1
[LiteratureReference:9926245] Drosophila Mitf regulates the V-ATPase and the lysosomal-autophagic pathway
[LiteratureReference:9730403] MITF-the first 25 years
[LiteratureReference:9858868] Novel roles for the MiTF/TFE family of transcription factors in organelle biogenesis, nutrient sensing, and energy homeostasis
[LiteratureReference:9858862] Rag GTPases mediate amino acid-dependent recruitment of TFEB and MITF to lysosomes
[LiteratureReference:9858860] Induction of melanogenesis by rapamycin in human MNT-1 melanoma cells
[LiteratureReference:9858864] WIPI1 coordinates melanogenic gene transcription and melanosome formation via TORC1 inhibition
modified[InstanceEdit:9859473] Rothfels, Karen, 2024-01-19
[InstanceEdit:9863246] Rothfels, Karen, 2024-02-28
[InstanceEdit:9910861] Rothfels, Karen, 2024-05-21
[InstanceEdit:9926426] Rothfels, Karen, 2024-11-01
[InstanceEdit:9927681] Rothfels, Karen, 2024-11-08
nameMITF-M binds the promoters of v-ATPase target genes
output[CandidateSet:9858892] MITF-M dimer:MITF-dependent v-ATPase target genes [nucleoplasm] [Homo sapiens]
precedingEvent
previousReviewStatus[ReviewStatus:9821383] three stars
releaseDate2024-03-27
reviewed[InstanceEdit:9863245] Arnheiter, Heinz, 2024-02-26
[InstanceEdit:9910860] de la Serna, Ivana L, 2024-05-21
[InstanceEdit:9927254] Vu, Hong Nhung, 2024-11-05
[InstanceEdit:9927252] Steingrímsson, Eiríkur, 2024-11-05
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9858908] R-HSA-9858883.3
summation[Summation:9858850] The v-ATPase is an evolutionarily conserved complex, closely...
(hasEvent)[Pathway:9857377] Regulation of MITF-M-dependent genes involved in lysosome biogenesis and autophagy [Homo sapiens]
(precedingEvent)[BlackBoxEvent:9858912] MITF-M-dependent ATP6V1C1 gene expression [Homo sapiens]
[BlackBoxEvent:9858913] MITF-M-dependent ATP6V0C gene expression [Homo sapiens]
[BlackBoxEvent:9858916] MITF-M-dependent ATP6V1H gene expression [Homo sapiens]
[BlackBoxEvent:9858918] MITF-M-dependent ATP6V1B2 gene expression [Homo sapiens]
[BlackBoxEvent:9858923] MITF-M-dependent ATP6V1E1 gene expression [Homo sapiens]
[BlackBoxEvent:9858924] MITF-M-dependent ATP6V1G1gene expression [Homo sapiens]
[BlackBoxEvent:9858928] MITF-M-dependent ATP6V1A gene expression [Homo sapiens]
[BlackBoxEvent:9858932] MITF-M-dependent ATP6V0D1 gene expression [Homo sapiens]
[BlackBoxEvent:9858940] MITF-M-dependent ATP6V0B gene expression [Homo sapiens]
[BlackBoxEvent:9858941] MITF-M-dependent ATP6V0E1 gene expression [Homo sapiens]
(updatedInstance)[_UpdateTracker:9910956] Update Tracker - [Reaction:9858883] MITF-M binds the promoters of v-ATPase target genes - v89:[modifyText]
[_UpdateTracker:9928390] Update Tracker - [Reaction:9858883] MITF-M binds the promoters of v-ATPase target genes - v91:[modifyText, removeLiteratureReference]
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