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Details on Person Mitochondrial lipoyltransferase 1 (LIPT1) catalyses the tran...
| Class:Id | Summation:9858751 |
|---|---|
| _displayName | Mitochondrial lipoyltransferase 1 (LIPT1) catalyses the tran... |
| _timestamp | 2024-01-14 09:24:29 |
| created | [InstanceEdit:9858750] Stephan, Ralf, 2024-01-14 |
| text | Mitochondrial lipoyltransferase 1 (LIPT1) catalyses the transfer of a lipoyl group from lipoyl-K107-GCSH to two lysine residues of the PDH complex subunit E2 (DLAT) (Fujiwara et al. 1999; Cao et al., 2018). Defects in LIPT1 reduce lipoylation of pyruvate dehydrogenase and alpha-ketoglutarate dehydrogenase, causing a cofactor disorder of mitochondrial energy metabolism (Soreze et al. 2013, Tort et al. 2014; Ni et al., 2019). |
| (summation) | [Reaction:9858752] LIPT1 transfers lipoyl group from lipoyl-GCSH to DLAT [Homo sapiens] |
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No pathways have been reviewed or authored by Mitochondrial lipoyltransferase 1 (LIPT1) catalyses the tran... (9858751)
