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Details on Person MITF-M-dependent PLK1 expression

Class:Id	BlackBoxEvent:9858636
_displayName	MITF-M-dependent PLK1 expression
_doRelease	TRUE
_timestamp	2024-11-08 15:57:34
authored	[InstanceEdit:9856650] Rothfels, Karen, 2023-12-21
compartment	[Compartment:7660] nucleoplasm [Compartment:70101] cytosol
created	[InstanceEdit:9858637] Rothfels, Karen, 2024-01-13
edited	[InstanceEdit:9856650] Rothfels, Karen, 2023-12-21
input	[EntityWithAccessionedSequence:4088289] PLK1 Gene [nucleoplasm] [Homo sapiens]
internalReviewed	[InstanceEdit:9859271] Orlic-Milacic, Marija, 2024-01-17
isChimeric	FALSE
literatureReference	[LiteratureReference:9854815] Essential role of microphthalmia transcription factor for DNA replication, mitosis and genomic stability in melanoma
modified	[InstanceEdit:9863248] Rothfels, Karen, 2024-02-28 [InstanceEdit:9910861] Rothfels, Karen, 2024-05-21 [InstanceEdit:9927681] Rothfels, Karen, 2024-11-08
name	MITF-M-dependent PLK1 expression
output	[EntityWithAccessionedSequence:164603] PLK1 [cytosol] [Homo sapiens]
precedingEvent	[Reaction:9858639] MITF-M dimer binds the PLK1 gene [Homo sapiens] [Reaction:9857375] MITF dimerizes [Homo sapiens]
previousReviewStatus	[ReviewStatus:9821383] three stars
regulatedBy	[PositiveGeneExpressionRegulation:9858622] Positive gene expression regulation by 'MITF-M dimer:PLK1 gene [nucleoplasm]'
regulationReference	[RegulationReference:9858648] Positive gene expression regulation by 'MITF-M dimer:PLK1 gene [nucleoplasm]' Essential role of microphthalmia transcription factor for DNA replication, mitosis and genomic stability in melanoma
releaseDate	2024-03-27
reviewed	[InstanceEdit:9863245] Arnheiter, Heinz, 2024-02-26 [InstanceEdit:9910860] de la Serna, Ivana L, 2024-05-21 [InstanceEdit:9927254] Vu, Hong Nhung, 2024-11-05 [InstanceEdit:9927252] Steingr�msson, Eir�kur, 2024-11-05
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9858660] R-HSA-9858636.3
summation	[Summation:9858611] PLK1 has been identified as a direct target of MITF activati...
(hasEvent)	[Pathway:9825892] Regulation of MITF-M-dependent genes involved in cell cycle and proliferation [Homo sapiens]
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No pathways have been reviewed or authored by MITF-M-dependent PLK1 expression (9858636)