Query author contributions in Reactome
Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.
If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.
Details on Person CCND1 expression in melanoma cells depends in part on the bi...
| Class:Id | Summation:9858601 |
|---|---|
| _displayName | CCND1 expression in melanoma cells depends in part on the bi... |
| _timestamp | 2024-01-19 17:56:20 |
| created | [InstanceEdit:9858610] Rothfels, Karen, 2024-01-13 |
| modified | [InstanceEdit:9859473] Rothfels, Karen, 2024-01-19 |
| text | CCND1 expression in melanoma cells depends in part on the binding of CTNNB1 to a cognate site in the CCND1 promoter, as assessed by ChIP and reporter gene assay. Consistent with this, mutation of the TCF/LEF binding site abrogates expression of the CCND1 reporter CTNNB1-dependent activation of CCND1 expression can be inhibited by recruitment of the HINT1 repressor along with co-repressors SIN3A and HDAC1 (Genovese et al, 2013). |
| (summation) | [Reaction:9858646] TCF/LEF:CTNNB1 binds the CCND1 gene [Homo sapiens] |
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No pathways have been reviewed or authored by CCND1 expression in melanoma cells depends in part on the bi... (9858601)
