Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Details on Person MITF-M-dependent CDK2 expression

Class:Id	BlackBoxEvent:9858566
_displayName	MITF-M-dependent CDK2 expression
_doRelease	TRUE
_timestamp	2024-11-08 15:57:09
authored	[InstanceEdit:9856650] Rothfels, Karen, 2023-12-21
compartment	[Compartment:7660] nucleoplasm [Compartment:70101] cytosol
created	[InstanceEdit:9858568] Rothfels, Karen, 2024-01-13
edited	[InstanceEdit:9856650] Rothfels, Karen, 2023-12-21
input	[EntityWithAccessionedSequence:9858551] CDK2 gene [nucleoplasm] [Homo sapiens]
internalReviewed	[InstanceEdit:9859271] Orlic-Milacic, Marija, 2024-01-17
isChimeric	FALSE
literatureReference	[LiteratureReference:9858465] Critical role of CDK2 for melanoma growth linked to its melanocyte-specific transcriptional regulation by MITF [LiteratureReference:9858511] Targeting CDK2 overcomes melanoma resistance against BRAF and Hsp90 inhibitors [LiteratureReference:9730403] MITF-the first 25 years
modified	[InstanceEdit:9863248] Rothfels, Karen, 2024-02-28 [InstanceEdit:9910861] Rothfels, Karen, 2024-05-21 [InstanceEdit:9927681] Rothfels, Karen, 2024-11-08
name	MITF-M-dependent CDK2 expression
output	[EntityWithAccessionedSequence:157440] CDK2 [cytosol] [Homo sapiens]
precedingEvent	[Reaction:9858560] MITF-M dimer binds the CDK2 gene [Homo sapiens] [Reaction:9857375] MITF dimerizes [Homo sapiens]
previousReviewStatus	[ReviewStatus:9821383] three stars
regulatedBy	[PositiveGeneExpressionRegulation:9858570] Positive gene expression regulation by 'MITF-M dimer:CDK2 gene [nucleoplasm]'
regulationReference	[RegulationReference:9858569] Positive gene expression regulation by 'MITF-M dimer:CDK2 gene [nucleoplasm]' Critical role of CDK2 for melanoma growth linked to its melanocyte-specific transcriptional regulation by MITF
releaseDate	2024-03-27
reviewed	[InstanceEdit:9863245] Arnheiter, Heinz, 2024-02-26 [InstanceEdit:9910860] de la Serna, Ivana L, 2024-05-21 [InstanceEdit:9927254] Vu, Hong Nhung, 2024-11-05 [InstanceEdit:9927252] Steingr�msson, Eir�kur, 2024-11-05
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9858573] R-HSA-9858566.3
summation	[Summation:9858549] CDK2 is expressed in the melanocyte lineage and in melanoma ...
(hasEvent)	[Pathway:9825892] Regulation of MITF-M-dependent genes involved in cell cycle and proliferation [Homo sapiens]
[Change default viewing format]

No pathways have been reviewed or authored by MITF-M-dependent CDK2 expression (9858566)