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Details on Person Based on a mouse model of hepatic steatosis, expression of t...
| Class:Id | Summation:9857993 |
|---|---|
| _displayName | Based on a mouse model of hepatic steatosis, expression of t... |
| _timestamp | 2024-04-12 13:18:18 |
| created | [InstanceEdit:9857988] Orlic-Milacic, Marija, 2024-01-09 |
| literatureReference | [LiteratureReference:9842041] Critical Roles of the Histone Methyltransferase MLL4/KMT2D in Murine Hepatic Steatosis Directed by ABL1 and PPARĪ³2 |
| modified | [InstanceEdit:9907275] Orlic-Milacic, Marija, 2024-04-05 [InstanceEdit:9907536] Orlic-Milacic, Marija, 2024-04-12 |
| text | Based on a mouse model of hepatic steatosis, expression of the PLIN2 gene, encoding Perilipin-2 that localizes to the lipid droplets, is directly stimulated by PPARG2 and the MLL4 complex and negatively regulated by imatinib, an inhibitor of ABL1 kinase and consequently and inhibitor of ABL1-promoted association of PPARG2 with the MLL4 complex (Kim et al. 2016). |
| (summation) | [BlackBoxEvent:9854140] PLIN2 gene expression is stimulated by PPARG2 and MLL4(MLL3) [Homo sapiens] |
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No pathways have been reviewed or authored by Based on a mouse model of hepatic steatosis, expression of t... (9857993)
