Reactome: A Curated Pathway Database
THIS SITE IS USED FOR CURATION AND TESTING
IT IS NOT STABLE, IS LINKED TO AN INCOMPLETE DATA SET, AND IS NOT MONITORED FOR PERFORMANCE. WE STRONGLY RECOMMEND THE USE OF OUR PUBLIC SITE

Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Name Email address

Details on Person HPDL dioxygenates HPPA

Class:IdReaction:9856718
_displayNameHPDL dioxygenates HPPA
_doReleaseTRUE
_timestamp2024-05-21 08:14:37
authored[InstanceEdit:9856598] Stephan, Ralf, 2023-12-20
catalystActivity[CatalystActivity:9856680] 4-hydroxymandelate synthase activity of HPDL:Fe2+ [mitochondrial matrix]
compartment[Compartment:5460] mitochondrial matrix
created[InstanceEdit:9856699] Stephan, Ralf, 2023-12-22
crossReference[DatabaseIdentifier:9856720] RHEA:21377
edited[InstanceEdit:9910825] Stephan, Ralf, 2024-05-21
input[SimpleEntity:9856684] HPP [mitochondrial matrix]
[SimpleEntity:113533] O2 [mitochondrial matrix]
internalReviewed[InstanceEdit:9857489] D'Eustachio, Peter, 2024-01-07
isChimericFALSE
literatureReference[LiteratureReference:9856597] Biosynthesis, Deficiency, and Supplementation of Coenzyme Q
[LiteratureReference:9856710] The polar oxy-metabolome reveals the 4-hydroxymandelate CoQ10 synthesis pathway
[LiteratureReference:9856701] Bi-allelic HPDL Variants Cause a Neurodegenerative Disease Ranging from Neonatal Encephalopathy to Adolescent-Onset Spastic Paraplegia
modified[InstanceEdit:9857488] Stephan, Ralf, 2024-01-07
[InstanceEdit:9859571] Stephan, Ralf, 2024-01-21
[InstanceEdit:9909266] Stephan, Ralf, 2024-05-02
[InstanceEdit:9909592] Stephan, Ralf, 2024-05-14
[InstanceEdit:9910562] Stephan, Ralf, 2024-05-15
[InstanceEdit:9910824] Stephan, Ralf, 2024-05-21
nameHPDL dioxygenates HPPA
output[SimpleEntity:9856722] 4-HMA [mitochondrial matrix]
[SimpleEntity:29376] CO2 [mitochondrial matrix]
precedingEvent
previousReviewStatus[ReviewStatus:9821383] three stars
releaseDate2024-06-15
reviewed[InstanceEdit:9909268] Pierrel, Fabien, 2024-05-02
[InstanceEdit:9909593] Marchi, Marco, 2024-05-14
[InstanceEdit:9910563] Tonello, Fiorella, 2024-05-15
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9856731] R-HSA-9856718.1
summation[Summation:9856721] Mitochondrial 4-hydroxyphenylpyruvate dioxygenase-like prote...
(hasEvent)[Pathway:2142789] Ubiquinol biosynthesis [Homo sapiens]
(precedingEvent)[Reaction:9856737] Unknown enzyme(s) process 4-HMA to 4-Hbz [Homo sapiens]
[Change default viewing format]
No pathways have been reviewed or authored by HPDL dioxygenates HPPA (9856718)