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Details on Person MITF-M dimer binds MYO5A gene
Class:Id Reaction:9856464
_displayName MITF-M dimer binds MYO5A gene
_doRelease TRUE
_timestamp 2024-11-08 15:56:09
authored [InstanceEdit:9856650] Rothfels, Karen, 2023-12-21
compartment [Compartment:7660] nucleoplasm
created [InstanceEdit:9856459] Rothfels, Karen, 2023-12-18
edited [InstanceEdit:9856650] Rothfels, Karen, 2023-12-21
input [EntityWithAccessionedSequence:9856434] MYO5A gene [nucleoplasm] [Homo sapiens] [Complex:9825710] MITF-M dimer [nucleoplasm] [Homo sapiens]
internalReviewed [InstanceEdit:9859271] Orlic-Milacic, Marija, 2024-01-17
isChimeric FALSE
literatureReference [LiteratureReference:9854815] Essential role of microphthalmia transcription factor for DNA replication, mitosis and genomic stability in melanoma [LiteratureReference:9732019] MYO5A Gene Is a Target of MITF in Melanocytes [LiteratureReference:9731980] Fifteen-year quest for microphthalmia-associated transcription factor target genes [LiteratureReference:9730403] MITF-the first 25 years [LiteratureReference:9856425] Rab27a: A key to melanosome transport in human melanocytes [LiteratureReference:9856429] Slac2-a/melanophilin, the missing link between Rab27 and myosin Va: implications of a tripartite protein complex for melanosome transport [LiteratureReference:9856394] Melanophilin directly links Rab27a and myosin Va through its distinct coiled-coil regions [LiteratureReference:9856421] Rab27A-binding protein Slp2-a is required for peripheral melanosome distribution and elongated cell shape in melanocytes [LiteratureReference:9856416] Rab GTPases and myosin motors in organelle motility [LiteratureReference:9856397] Melanosomes on the move: a model to understand organelle dynamics
modified [InstanceEdit:9857592] Rothfels, Karen, 2024-01-07 [InstanceEdit:9858741] Rothfels, Karen, 2024-01-14 [InstanceEdit:9863246] Rothfels, Karen, 2024-02-28 [InstanceEdit:9910861] Rothfels, Karen, 2024-05-21 [InstanceEdit:9927681] Rothfels, Karen, 2024-11-08
name MITF-M dimer binds MYO5A gene
output [Complex:9856445] MITF-M dimer:MYO5A gene [nucleoplasm] [Homo sapiens]
precedingEvent
previousReviewStatus [ReviewStatus:9821383] three stars
releaseDate 2024-03-27
reviewed [InstanceEdit:9863245] Arnheiter, Heinz, 2024-02-26 [InstanceEdit:9910860] de la Serna, Ivana L, 2024-05-21 [InstanceEdit:9927254] Vu, Hong Nhung, 2024-11-05 [InstanceEdit:9927252] Steingrímsson, Eiríkur, 2024-11-05
reviewStatus [ReviewStatus:9821382] five stars
species [Species:48887] Homo sapiens
stableIdentifier [StableIdentifier:9856470] R-HSA-9856464.3
summation [Summation:9856452] MITF-M binds to the MYO5A promoter to stimulate transcriptio...
(hasEvent) [Pathway:9824585] Regulation of MITF-M-dependent genes involved in pigmentation [Homo sapiens]
(precedingEvent) [BlackBoxEvent:9856462] MITF-M-dependent MYO5A expression [Homo sapiens]
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