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Details on Person MITF-M-dependent GPR143 expression

Class:IdBlackBoxEvent:9856053
_displayNameMITF-M-dependent GPR143 expression
_doReleaseTRUE
_timestamp2024-11-08 15:57:20
authored[InstanceEdit:9856650] Rothfels, Karen, 2023-12-21
compartment[Compartment:5668575] melanosome membrane
[Compartment:7660] nucleoplasm
created[InstanceEdit:9856054] Rothfels, Karen, 2023-12-09
edited[InstanceEdit:9856650] Rothfels, Karen, 2023-12-21
input[EntityWithAccessionedSequence:9856045] GPR143 gene [nucleoplasm] [Homo sapiens]
internalReviewed[InstanceEdit:9859271] Orlic-Milacic, Marija, 2024-01-17
isChimericFALSE
literatureReference[LiteratureReference:9856014] The ocular albinism type 1 (OA1) gene controls melanosome maturation and size
[LiteratureReference:8851293] The ocular albinism type 1 (OA1) protein and the evidence for an intracellular signal transduction system involved in melanosome biogenesis
[LiteratureReference:9856009] The microphthalmia transcription factor (Mitf) controls expression of the ocular albinism type 1 gene: link between melanin synthesis and melanosome biogenesis
[LiteratureReference:9856020] The ocular albinism type 1 protein, an intracellular G protein-coupled receptor, regulates melanosome transport in pigment cells
[LiteratureReference:9856013] The ocular albinism type 1 (OA1) G-protein-coupled receptor functions with MART-1 at early stages of melanogenesis to control melanosome identity and composition
[LiteratureReference:9854815] Essential role of microphthalmia transcription factor for DNA replication, mitosis and genomic stability in melanoma
[LiteratureReference:9731980] Fifteen-year quest for microphthalmia-associated transcription factor target genes
modified[InstanceEdit:9863248] Rothfels, Karen, 2024-02-28
[InstanceEdit:9910861] Rothfels, Karen, 2024-05-21
[InstanceEdit:9927681] Rothfels, Karen, 2024-11-08
nameMITF-M-dependent GPR143 expression
output[EntityWithAccessionedSequence:8851292] GPR143 [plasma membrane] [Homo sapiens]
precedingEvent
previousReviewStatus[ReviewStatus:9821383] three stars
regulatedBy[PositiveGeneExpressionRegulation:9856046] Positive gene expression regulation by 'MITF-M:GPR143 gene [nucleoplasm]'
regulationReference[RegulationReference:9856051] Positive gene expression regulation by 'MITF-M:GPR143 gene [nucleoplasm]' Essential role of microphthalmia transcription factor for DNA replication, mitosis and genomic stability in melanoma
releaseDate2024-03-27
reviewed[InstanceEdit:9863245] Arnheiter, Heinz, 2024-02-26
[InstanceEdit:9910860] de la Serna, Ivana L, 2024-05-21
[InstanceEdit:9927254] Vu, Hong Nhung, 2024-11-05
[InstanceEdit:9927252] Steingrímsson, Eiríkur, 2024-11-05
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9856058] R-HSA-9856053.3
summation[Summation:9856027] GPR143 encodes a GPCR that, with MLANA, plays a role in the ...
(hasEvent)[Pathway:9824585] Regulation of MITF-M-dependent genes involved in pigmentation [Homo sapiens]
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No pathways have been reviewed or authored by MITF-M-dependent GPR143 expression (9856053)
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