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Details on Person USF1 is phosphorylated by p-MAPK14

Class:IdReaction:9855910
_displayNameUSF1 is phosphorylated by p-MAPK14
_doReleaseTRUE
_timestamp2024-11-08 15:58:52
authored[InstanceEdit:9856650] Rothfels, Karen, 2023-12-21
catalystActivity[CatalystActivity:9855901] protein serine/threonine kinase activity of p-T180,Y182-MAPK14 [nucleoplasm]
catalystActivityReference[CatalystActivityReference:9855906] protein serine/threonine kinase activity of p-T180,Y182-MAPK14 [nucleoplasm] The Usf-1 transcription factor is a novel target for the stress-responsive p38 kinase and mediates UV-induced Tyrosinase expression
compartment[Compartment:7660] nucleoplasm
created[InstanceEdit:9855907] Rothfels, Karen, 2023-12-07
edited[InstanceEdit:9856650] Rothfels, Karen, 2023-12-21
input[Complex:9855889] USF1 dimer [nucleoplasm] [Homo sapiens]
[SimpleEntity:29358] ATP [nucleoplasm]
[SimpleEntity:29358] ATP [nucleoplasm]
internalReviewed[InstanceEdit:9859271] Orlic-Milacic, Marija, 2024-01-17
isChimericFALSE
literatureReference[LiteratureReference:9855320] Recognition of the E-C4 element from the C4 complement gene promoter by the upstream stimulatory factor-1 transcription factor
[LiteratureReference:9855332] The Usf-1 transcription factor is a novel target for the stress-responsive p38 kinase and mediates UV-induced Tyrosinase expression
[LiteratureReference:9855344] UV-induced expression of key component of the tanning process, the POMC and MC1R genes, is dependent on the p-38-activated upstream stimulating factor-1 (USF-1)
[LiteratureReference:9855328] Target gene specificity of USF-1 is directed via p38-mediated phosphorylation-dependent acetylation
modified[InstanceEdit:9855917] Rothfels, Karen, 2023-12-07
[InstanceEdit:9863246] Rothfels, Karen, 2024-02-28
[InstanceEdit:9907153] Rothfels, Karen, 2024-04-04
[InstanceEdit:9909022] Rothfels, Karen, 2024-04-25
[InstanceEdit:9910861] Rothfels, Karen, 2024-05-21
[InstanceEdit:9927682] Rothfels, Karen, 2024-11-08
nameUSF1 is phosphorylated by p-MAPK14
output[Complex:9855890] pT153 USF1 dimer [nucleoplasm] [Homo sapiens]
[SimpleEntity:113582] ADP [nucleoplasm]
[SimpleEntity:113582] ADP [nucleoplasm]
previousReviewStatus[ReviewStatus:9821383] three stars
releaseDate2024-06-15
reviewed[InstanceEdit:9910860] de la Serna, Ivana L, 2024-05-21
[InstanceEdit:9927254] Vu, Hong Nhung, 2024-11-05
[InstanceEdit:9927252] Steingrímsson, Eiríkur, 2024-11-05
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9855913] R-HSA-9855910.2
summation[Summation:9855880] Upstream Stimulatory Factor 1 (USF1) is a transcription fact...
(hasEvent)[Pathway:9824585] Regulation of MITF-M-dependent genes involved in pigmentation [Homo sapiens]
(precedingEvent)[Reaction:9855908] p-T153 USF1 dimer binds the TYR promoter [Homo sapiens]
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No pathways have been reviewed or authored by USF1 is phosphorylated by p-MAPK14 (9855910)
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