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Details on Person Upstream Stimulatory Factor 1 (USF1) is a transcription fact...
| Class:Id | Summation:9855880 |
|---|---|
| _displayName | Upstream Stimulatory Factor 1 (USF1) is a transcription fact... |
| _timestamp | 2024-01-19 02:15:44 |
| created | [InstanceEdit:9855875] Rothfels, Karen, 2023-12-07 |
| modified | [InstanceEdit:9859417] Rothfels, Karen, 2024-01-19 |
| text | Upstream Stimulatory Factor 1 (USF1) is a transcription factor that binds as a dimer to symmetrical E-box sequences (5'-CACGTG-3'). It has been identified with MITF-M as a regulator of TYR gene expression downstream of UV signaling (Galibert et al, 1998; Galibert et al, 2001; Corre et al, 2004; Corre et al, 2009). MAPK14 (also known as p38 alpha)-dependent phosphorylation of USF1 at residue T153 is promoted by UV stimulation in melanoma cells and enhances DNA-binding at the TYR promoter as assessed by ChIP and EMSA (Galibert et al, 2001). |
| (summation) | [Reaction:9855910] USF1 is phosphorylated by p-MAPK14 [Homo sapiens] |
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No pathways have been reviewed or authored by Upstream Stimulatory Factor 1 (USF1) is a transcription fact... (9855880)
