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Details on Person serine-type endopeptidase activity of KLKB1:KNG1:(C1QBP,C1QBP:KRT1, PLAUR:KRT1):FXII [plasma membrane]

Class:IdCatalystActivity:9855680
_displayNameserine-type endopeptidase activity of KLKB1:KNG1:(C1QBP,C1QBP:KRT1, PLAUR:KRT1):FXII [plasma membrane]
_timestamp2024-04-25 21:19:42
activeUnit[EntityWithAccessionedSequence:158214] factor XII [plasma membrane] [Homo sapiens]
activity[GO_MolecularFunction:1683] serine-type endopeptidase activity
created[InstanceEdit:9855678] Shamovsky, Veronica, 2023-12-07
modified[InstanceEdit:9857982] Shamovsky, Veronica, 2024-01-09
[InstanceEdit:9909040] Shamovsky, Veronica, 2024-04-25
[InstanceEdit:9909910] Weiser, Joel, 2024-05-14
[InstanceEdit:9909910] Weiser, Joel, 2024-05-14
[InstanceEdit:9917728] Weiser, Joel, 2024-08-09
[InstanceEdit:9917728] Weiser, Joel, 2024-08-09
[InstanceEdit:9926726] Weiser, Joel, 2024-11-03
[InstanceEdit:9926726] Weiser, Joel, 2024-11-03
[InstanceEdit:9939161] Weiser, Joel, 2025-02-21
[InstanceEdit:9939161] Weiser, Joel, 2025-02-21
[InstanceEdit:9948552] Weiser, Joel, 2025-05-21
[InstanceEdit:9948552] Weiser, Joel, 2025-05-21
[InstanceEdit:9963749] Weiser, Joel, 2025-08-15
[InstanceEdit:9963749] Weiser, Joel, 2025-08-15
[InstanceEdit:9970792] Weiser, Joel, 2025-10-31
[InstanceEdit:9970792] Weiser, Joel, 2025-10-31
[InstanceEdit:9983308] Weiser, Joel, 2026-02-22
[InstanceEdit:9983308] Weiser, Joel, 2026-02-22
[InstanceEdit:9989150] Weiser, Joel, 2026-05-15
[InstanceEdit:9989150] Weiser, Joel, 2026-05-15
physicalEntity[Complex:9857822] KLKB1:KNG1:(C1QBP,C1QBP:KRT1, PLAUR:KRT1):FXII [plasma membrane] [Homo sapiens]
(catalystActivity)[Reaction:9655840] FXIIa is cleaved to β-FXIIa [Homo sapiens]
[Reaction:9857814] prekallikrein:kininogen:cell surface receptor:factor XII -> factor XIIa + prekallikrein:kininogen:cell surface receptor (FXII autocatalysis on the cell surface) [Homo sapiens]
[Reaction:9909048] prekallikrein:kininogen:cell surface receptor:factor XII -> kallikrein:kininogen:cell surface receptor:factor XII (FXII catalyst) [Homo sapiens]
[CatalystActivityReference:9857821] serine-type endopeptidase activity of FXII:C1QBP,C1QBP:KRT1, PLAUR:KRT1 [plasma membrane] Factor XII-dependent contact activation on endothelial cells and binding proteins gC1qR and cytokeratin 1
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No pathways have been reviewed or authored by serine-type endopeptidase activity of KLKB1:KNG1:(C1QBP,C1QBP:KRT1, PLAUR:KRT1):FXII [plasma membrane] (9855680)