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Details on Person Piezo2 trimer transports cations from the extracellular region to the cytosol

Class:Id	Reaction:9855147
_displayName	Piezo2 trimer transports cations from the extracellular region to the cytosol
_timestamp	2024-03-24 14:54:07
authored	[InstanceEdit:9855110] May, Bruce, 2023-11-18
catalystActivity	[CatalystActivity:9855028] mechanosensitive monoatomic cation channel activity of Piezo2 trimer [plasma membrane]
compartment	[Compartment:984] extracellular region [Compartment:876] plasma membrane [Compartment:70101] cytosol
created	[InstanceEdit:9855036] May, Bruce, 2023-11-29
edited	[InstanceEdit:9855110] May, Bruce, 2023-11-18
input	[DefinedSet:9855128] Ca2+,K+,Mg2+,Na+ [extracellular region]
isChimeric	FALSE
literatureReference	[LiteratureReference:9855121] Piezo1 and Piezo2 are essential components of distinct mechanically activated cation channels [LiteratureReference:9855033] Piezo2 is the major transducer of mechanical forces for touch sensation in mice [LiteratureReference:9855086] Merkel cells transduce and encode tactile stimuli to drive Aβ-afferent impulses
modified	[InstanceEdit:9866211] May, Bruce, 2024-03-24
name	Piezo2 trimer transports cations from the extracellular region to the cytosol
output	[DefinedSet:9855085] Ca2+,K+,Mg2+,Na+ [cytosol]
species	[Species:48892] Mus musculus
stableIdentifier	[StableIdentifier:9855187] R-MMU-9855147.1
(inferredFrom)	[Reaction:9855038] PIEZO2 trimer transports cations from the extracellular region to the cytosol [Homo sapiens]
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