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Details on Person FAD attaches to SDHA

Class:IdReaction:9854672
_displayNameFAD attaches to SDHA
_doReleaseTRUE
_timestamp2025-08-13 19:23:32
authored[InstanceEdit:9854482] Stephan, Ralf, 2023-11-27
catalystActivity[CatalystActivity:9956931] FAD binding activity of SDHA [mitochondrial matrix]
compartment[Compartment:5460] mitochondrial matrix
created[InstanceEdit:9854696] Stephan, Ralf, 2023-11-28
edited[InstanceEdit:9861216] D'Eustachio, Peter, 2024-02-15
input[EntityWithAccessionedSequence:9854690] SDHA [mitochondrial matrix] [Homo sapiens]
[SimpleEntity:113596] FAD [mitochondrial matrix]
internalReviewed[InstanceEdit:9856153] D'Eustachio, Peter, 2023-12-12
[InstanceEdit:9956934] D'Eustachio, Peter, 2025-06-16
isChimericFALSE
literatureReference[LiteratureReference:9854676] How an assembly factor enhances covalent FAD attachment to the flavoprotein subunit of complex II
[LiteratureReference:9854688] SDH5, a gene required for flavination of succinate dehydrogenase, is mutated in paraganglioma
modified[InstanceEdit:9854978] Stephan, Ralf, 2023-11-29
[InstanceEdit:9856154] Stephan, Ralf, 2023-12-12
[InstanceEdit:9859506] Stephan, Ralf, 2024-01-20
[InstanceEdit:9861217] D'Eustachio, Peter, 2024-02-15
[InstanceEdit:9956930] D'Eustachio, Peter, 2025-06-16
[InstanceEdit:9956933] D'Eustachio, Peter, 2025-06-16
[InstanceEdit:9963234] D'Eustachio, Peter, 2025-08-13
nameFAD attaches to SDHA
output[EntityWithAccessionedSequence:70983] FAD-SDHA [mitochondrial matrix] [Homo sapiens]
previousReviewStatus[ReviewStatus:9821385] four stars
regulatedBy[Requirement:9854702] Requirement by 'SDHAF2 [mitochondrial matrix]'
[PositiveRegulation:9854700] Positive regulation by 'FUMA [mitochondrial matrix]'
releaseDate2024-03-27
reviewed[InstanceEdit:9861215] Hill, David P, 2024-02-15
[InstanceEdit:9963235] Hill, David P, 2025-08-13
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9854707] R-HSA-9854672.2
structureModified[InstanceEdit:9956930] D'Eustachio, Peter, 2025-06-16
summation[Summation:9854703] Flavin adenine dinucleotide (FAD) binds covalently and non-e...
(hasEvent)[Pathway:9854311] Maturation of TCA enzymes and regulation of TCA cycle [Homo sapiens]
(precedingEvent)[Reaction:9854961] SDHAF4 binds to FAD-SDHA [Homo sapiens]
(updatedInstance)[_UpdateTracker:9964723] Update Tracker - [Reaction:9854672] FAD attaches to SDHA - v94:[removeCatalystActivity]
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No pathways have been reviewed or authored by FAD attaches to SDHA (9854672)