Query author contributions in Reactome
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Details on Person NAD-dependent protein deacetylase sirtuin-3 (SIRT-3) deacety...
| Class:Id | Summation:9854459 |
|---|---|
| _displayName | NAD-dependent protein deacetylase sirtuin-3 (SIRT-3) deacety... |
| _timestamp | 2023-12-07 09:07:55 |
| created | [InstanceEdit:9854461] Stephan, Ralf, 2023-11-27 |
| modified | [InstanceEdit:9855772] Stephan, Ralf, 2023-12-07 |
| text | NAD-dependent protein deacetylase sirtuin-3 (SIRT-3) deacetylates lysine-413 residue of IDH2, restoring its enzymatic activity. Since IDH2 is the main producer of NADPH, SIRT3 has a direct effect on the antioxidant level in mitochondria (Lombard et al., 2007; Yu et al., 2012; Chen et al., 2021; reviewed in Gao & Shen, 2023). |
| (summation) | [Reaction:9854463] SIRT3 deacetylates AcK-IDH2 dimer [Homo sapiens] |
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No pathways have been reviewed or authored by NAD-dependent protein deacetylase sirtuin-3 (SIRT-3) deacety... (9854459)
