Reactome: A Curated Pathway Database
THIS SITE IS USED FOR CURATION AND TESTING
IT IS NOT STABLE, IS LINKED TO AN INCOMPLETE DATA SET, AND IS NOT MONITORED FOR PERFORMANCE. WE STRONGLY RECOMMEND THE USE OF OUR PUBLIC SITE

Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Name Email address

Details on Person Pancreatic alpha cells produce glucagon, a hormone that incr...

Class:IdSummation:9854440
_displayNamePancreatic alpha cells produce glucagon, a hormone that incr...
_timestamp2024-07-05 13:19:43
created[InstanceEdit:9854443] Orlic-Milacic, Marija, 2023-11-26
literatureReference[LiteratureReference:9915421] Lineage dynamics of murine pancreatic development at single-cell resolution
modified[InstanceEdit:9915424] Orlic-Milacic, Marija, 2024-07-05
textPancreatic alpha cells produce glucagon, a hormone that increases blood glucose levels by promoting the breakdown of glycogen in the liver. By lineage tracing in developing mouse pancreas, 100% of alpha, beta, and delta cells in E14.5, E17.5, and adulthood (6 weeks) are derived from progeny of Ngn3-positive cells expressing high level of transcription factor Fev (Byrnes et al. 2018).
(summation)[CellDevelopmentStep:9853411] Pancreatic alpha/PP late endocrine progenitor differentiates into pancreatic alpha cell [Homo sapiens]
[Change default viewing format]
No pathways have been reviewed or authored by Pancreatic alpha cells produce glucagon, a hormone that incr... (9854440)