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Details on Person All enzymes of the TCA cycle are highly acetylated at multip...
| Class:Id | Summation:9854411 |
|---|---|
| _displayName | All enzymes of the TCA cycle are highly acetylated at multip... |
| _timestamp | 2023-12-07 09:07:25 |
| created | [InstanceEdit:9854421] Stephan, Ralf, 2023-11-26 |
| modified | [InstanceEdit:9855772] Stephan, Ralf, 2023-12-07 |
| text | All enzymes of the TCA cycle are highly acetylated at multiple lysine residues (reviewed in Zhao et al., 2010). The effects of this modification on enzyme activity are largely unknown. In the case of IDH2, however, acetylation by ACAT1 homotetramer at lysine 413 abolishes its activity (Chen et al., 2021), and thereby plays a major role in TCA cycle regulation. |
| (summation) | [Reaction:9854415] ACAT1 tetramer acetylates IDH2 dimer [Homo sapiens] |
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No pathways have been reviewed or authored by All enzymes of the TCA cycle are highly acetylated at multip... (9854411)
