Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Details on Person CSKMT methylates Citrate Synthase

Class:Id	Reaction:9854315
_displayName	CSKMT methylates Citrate Synthase
_doRelease	TRUE
_timestamp	2024-02-16 19:57:28
authored	[InstanceEdit:9854297] Stephan, Ralf, 2023-11-25
catalystActivity	[CatalystActivity:9854316] protein-lysine N-methyltransferase activity of CSKMT [mitochondrial matrix]
compartment	[Compartment:5460] mitochondrial matrix
created	[InstanceEdit:9854323] Stephan, Ralf, 2023-11-25
crossReference	[DatabaseIdentifier:9854324] RHEA:55544 [DatabaseIdentifier:9854328] RHEA:55548 [DatabaseIdentifier:9854320] RHEA:55552
edited	[InstanceEdit:9861216] D'Eustachio, Peter, 2024-02-15
input	[DefinedSet:9854325] Methylated(n) CS dimer [mitochondrial matrix] [Homo sapiens] [SimpleEntity:9854319] S-adenosyl-L-methionine [mitochondrial matrix] [SimpleEntity:9854319] S-adenosyl-L-methionine [mitochondrial matrix]
internalReviewed	[InstanceEdit:9861214] D'Eustachio, Peter, 2024-02-15
isChimeric	FALSE
literatureReference	[LiteratureReference:9854357] Uncovering human METTL12 as a mitochondrial methyltransferase that modulates citrate synthase activity through metabolite-sensitive lysine methylation [LiteratureReference:9854354] Human METTL12 is a mitochondrial methyltransferase that modifies citrate synthase [LiteratureReference:9854352] Methyltransferase-like proteins in cancer biology and potential therapeutic targeting
modified	[InstanceEdit:9854355] Stephan, Ralf, 2023-11-26 [InstanceEdit:9854709] Stephan, Ralf, 2023-11-28 [InstanceEdit:9856154] Stephan, Ralf, 2023-12-12 [InstanceEdit:9859506] Stephan, Ralf, 2024-01-20 [InstanceEdit:9861205] D'Eustachio, Peter, 2024-02-14 [InstanceEdit:9861207] D'Eustachio, Peter, 2024-02-14 [InstanceEdit:9861217] D'Eustachio, Peter, 2024-02-15 [InstanceEdit:9861238] D'Eustachio, Peter, 2024-02-15 [InstanceEdit:9861239] D'Eustachio, Peter, 2024-02-15 [InstanceEdit:9861365] D'Eustachio, Peter, 2024-02-16
name	CSKMT methylates Citrate Synthase
output	[DefinedSet:9854313] Methylated(n+1) CS dimer [mitochondrial matrix] [Homo sapiens] [SimpleEntity:113529] H+ [mitochondrial matrix] [SimpleEntity:113529] H+ [mitochondrial matrix] [SimpleEntity:9854312] S-adenosyl-L-homocysteine [mitochondrial matrix] [SimpleEntity:9854312] S-adenosyl-L-homocysteine [mitochondrial matrix]
previousReviewStatus	[ReviewStatus:9821383] three stars
regulatedBy	[NegativeRegulation:9854353] Negative regulation by 'OA [mitochondrial matrix]' [NegativeRegulation:9861204] Negative regulation by 'S-adenosyl-L-homocysteine [mitochondrial matrix]'
regulationReference	[RegulationReference:9861203] Negative regulation by 'S-adenosyl-L-homocysteine [mitochondrial matrix]' Uncovering human METTL12 as a mitochondrial methyltransferase that modulates citrate synthase activity through metabolite-sensitive lysine methylation
releaseDate	2024-03-27
reviewed	[InstanceEdit:9861366] Hill, David P, 2024-02-16
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9854343] R-HSA-9854315.1
structureModified	[InstanceEdit:9854355] Stephan, Ralf, 2023-11-26 [InstanceEdit:9861205] D'Eustachio, Peter, 2024-02-14 [InstanceEdit:9861207] D'Eustachio, Peter, 2024-02-14
summation	[Summation:9854348] (Citrate-synthase)-lysyl-methyltransferase (CSKMT, METTL12) ...
(hasEvent)	[Pathway:9854311] Maturation of TCA enzymes and regulation of TCA cycle [Homo sapiens]
(precedingEvent)	[Reaction:70975] CS acetylates OA to citrate [Homo sapiens]
[Change default viewing format]

No pathways have been reviewed or authored by CSKMT methylates Citrate Synthase (9854315)