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Details on Person PLIN2 gene expression is stimulated by PPARG2 and MLL4(MLL3)

Class:Id	BlackBoxEvent:9854140
_displayName	PLIN2 gene expression is stimulated by PPARG2 and MLL4(MLL3)
_doRelease	FALSE
_timestamp	2024-08-14 14:36:48
created	[InstanceEdit:9854138] Orlic-Milacic, Marija, 2023-11-22
edited	[InstanceEdit:9917569] Orlic-Milacic, Marija, 2024-08-07
input	[EntityWithAccessionedSequence:5649938] PLIN2 gene [nucleoplasm] [Homo sapiens]
isChimeric	FALSE
modified	[InstanceEdit:9858002] Orlic-Milacic, Marija, 2024-01-09 [InstanceEdit:9917569] Orlic-Milacic, Marija, 2024-08-07 [InstanceEdit:9917571] Orlic-Milacic, Marija, 2024-08-07 [InstanceEdit:9918134] Orlic-Milacic, Marija, 2024-08-14
name	PLIN2 gene expression is stimulated by PPARG2 and MLL4(MLL3)
output	[EntityWithAccessionedSequence:9613345] PLIN2 [lipid droplet] [Homo sapiens]
precedingEvent	[BlackBoxEvent:9851879] MLL4-ASCOM,(MLL3-ASCOM) monomethylates nucleosomes at regulatory elements of steatotic genes [Homo sapiens] [BlackBoxEvent:9851871] MLL4-ASCOM,(MLL3-ASCOM) is recruited to PPARG2-bound regulatory elements of steatotic genes [Homo sapiens]
regulatedBy	[PositiveGeneExpressionRegulation:9854137] Positive gene expression regulation by 'PPARG natural ligands:p-Y78,Y102-PPARG2:RXRA natural ligands:RXRA:Coactivators:PLIN2 gene:H3K4me1-nucleosomes:MLL4-ASCOM,(MLL3-ASCOM)'
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9854147] R-HSA-9854140.1
summation	[Summation:9857993] Based on a mouse model of hepatic steatosis, expression of t...
(hasEvent)	[Pathway:9851812] MLL3 and MLL4 regulate expression of PPARG target genes in hepatic steatosis_not ready for review_merged with adipogenesis [Homo sapiens]
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No pathways have been reviewed or authored by PLIN2 gene expression is stimulated by PPARG2 and MLL4(MLL3) (9854140)