Query author contributions in Reactome
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Details on Person Dihydrolipoyl succinyl transferase (DLST), the E2 component ...
| Class:Id | Summation:9853764 |
|---|---|
| _displayName | Dihydrolipoyl succinyl transferase (DLST), the E2 component ... |
| _timestamp | 2023-11-21 10:21:23 |
| created | [InstanceEdit:9853770] Stephan, Ralf, 2023-11-21 |
| text | Dihydrolipoyl succinyl transferase (DLST), the E2 component of the 2-oxoglutarate dehydrogenase metabolon, self-associates into a cubic octamer of homotrimers. The trimer appears to be the minimal conformation for optimal activity. It transfers the succinyl moiety bound to one of its N6-dihydrolipoyllysine residues onto the substrate CoA (Nakano et al., 1994; Nagy et al., 2021). Mutations in DLST can lead to benign pheochromocytomas and paragangliomas (PGL7; MIM:618475; Remacha et al., 2019). |
| (summation) | [Reaction:9853512] DLST transfers succinyl to CoA [Homo sapiens] |
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No pathways have been reviewed or authored by Dihydrolipoyl succinyl transferase (DLST), the E2 component ... (9853764)
