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Details on Person Thrombin binds to GP1b:IX:V (replace 429529?)

Class:Id	Reaction:9853533
_displayName	Thrombin binds to GP1b:IX:V (replace 429529?)
_doRelease	FALSE
_timestamp	2023-11-21 10:34:00
compartment	[Compartment:984] extracellular region [Compartment:876] plasma membrane
created	[InstanceEdit:9853534] Shamovsky, Veronica, 2023-11-17
input	[Complex:156786] activated thrombin (factor IIa) [extracellular region] [Homo sapiens] [Complex:9823506] GP1BA:GP1BB:GP9:GP5:VWF:collagen type I [plasma membrane] [Homo sapiens]
literatureReference	[LiteratureReference:429530] Crystal structure of the GpIbalpha-thrombin complex essential for platelet aggregation [LiteratureReference:9853867] Binding of alpha-thrombin to surface-anchored platelet glycoprotein Ib(alpha) sulfotyrosines through a two-site mechanism involving exosite I
modified	[InstanceEdit:9853866] Shamovsky, Veronica, 2023-11-21
name	Thrombin binds to GP1b:IX:V (replace 429529?)
output	[Complex:9853536] FIIa:GP1BA:GP1BB:GP9:GP5:VWF:collagen type I [plasma membrane] [Homo sapiens]
precedingEvent	[Reaction:9823065] GPIb:IX:V binds to VWF multimer:collagen [Homo sapiens] [Reaction:9822539] VWF multimer binds to collagen type I [Homo sapiens]
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9853541] R-HSA-9853533.1
summation	[Summation:9853860] The GPIB alpha subunit binds thrombin at a site that include...
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