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Details on Person PPP1CC dephosphorylates PLK1

Class:IdReaction:9853385
_displayNamePPP1CC dephosphorylates PLK1
_doReleaseTRUE
_timestamp2024-05-16 11:58:39
authored[InstanceEdit:9851977] Orlic-Milacic, Marija, 2023-11-02
catalystActivity[CatalystActivity:9853438] protein serine/threonine phosphatase activity of PPP1CC [cytosol]
compartment[Compartment:70101] cytosol
created[InstanceEdit:9853378] Orlic-Milacic, Marija, 2023-11-15
edited[InstanceEdit:9863557] Orlic-Milacic, Marija, 2024-03-01
input[EntityWithAccessionedSequence:3000318] p-T210-PLK1 [cytosol] [Homo sapiens]
[SimpleEntity:29356] H2O [cytosol]
internalReviewed[InstanceEdit:9853658] Matthews, Lisa, 2023-11-16
isChimericFALSE
literatureReference[LiteratureReference:9851945] Feedback control of PLK1 by Apolo1 ensures accurate chromosome segregation
modified[InstanceEdit:9853442] Orlic-Milacic, Marija, 2023-11-15
[InstanceEdit:9853453] Orlic-Milacic, Marija, 2023-11-15
[InstanceEdit:9853659] Orlic-Milacic, Marija, 2023-11-20
[InstanceEdit:9863562] Orlic-Milacic, Marija, 2024-03-01
[InstanceEdit:9909010] Orlic-Milacic, Marija, 2024-04-25
[InstanceEdit:9910672] Orlic-Milacic, Marija, 2024-05-16
namePPP1CC dephosphorylates PLK1
negativePrecedingEvent[NegativePrecedingEvent:9910670] Futile Cycle: PLK1 phosphorylates FIRMM at S744
output[EntityWithAccessionedSequence:164603] PLK1 [cytosol] [Homo sapiens]
[SimpleEntity:29372] Pi [cytosol]
previousReviewStatus[ReviewStatus:9821383] three stars
regulatedBy[NegativeRegulation:9853433] Negative regulation by 'FIRRM:PPP1CC [cytosol]'
releaseDate2024-03-27
reviewed[InstanceEdit:9863560] Liu, Xing, 2024-03-01
[InstanceEdit:9863558] Yao, Xuebiao, 2024-03-01
[InstanceEdit:9909004] Orthwein, Alexandre, 2024-04-26
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9853395] R-HSA-9853385.2
structureModified[InstanceEdit:9853442] Orlic-Milacic, Marija, 2023-11-15
summation[Summation:9853447] PP1gamma (PPP1CC), a kinetochore component, dephosphorylates...
(hasEvent)[Pathway:2500257] Resolution of Sister Chromatid Cohesion [Homo sapiens]
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No pathways have been reviewed or authored by PPP1CC dephosphorylates PLK1 (9853385)