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Details on Person Coactivators are recruited to liganded PPARG2:RXRA dimers

Class:Id	BlackBoxEvent:9851863
_displayName	Coactivators are recruited to liganded PPARG2:RXRA dimers
_doRelease	FALSE
_timestamp	2025-11-04 00:58:16
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9851864] Orlic-Milacic, Marija, 2023-11-01
edited	[InstanceEdit:9917569] Orlic-Milacic, Marija, 2024-08-07
input	[DefinedSet:9851857] PPARG ligands:p-Y78,Y102-PPARG2:RXRA ligands:RXRA heterodimer:steatotic target genes:nucleosome [nucleoplasm] [Homo sapiens] [CandidateSet:9970995] (NCOA1, NCOA2, NCOA3) [nucleoplasm] [Homo sapiens]
isChimeric	FALSE
modified	[InstanceEdit:9917569] Orlic-Milacic, Marija, 2024-08-07 [InstanceEdit:9917571] Orlic-Milacic, Marija, 2024-08-07 [InstanceEdit:9918134] Orlic-Milacic, Marija, 2024-08-14 [InstanceEdit:9970998] Orlic-Milacic, Marija, 2025-11-04
name	Coactivators are recruited to liganded PPARG2:RXRA dimers
output	[DefinedSet:9851862] PPARG ligands:p-Y78,Y102-PPARG2:RXRA ligands:RXRA:coactivators:steatotic target genes:nucleosome [nucleoplasm] [Homo sapiens]
precedingEvent	[BlackBoxEvent:9851855] Corepressors are released from liganded PPARG2:RXRA dimers [Homo sapiens] [BlackBoxEvent:9851839] RXRA binds ligands [Homo sapiens]
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9851866] R-HSA-9851863.1
structureModified	[InstanceEdit:9970998] Orlic-Milacic, Marija, 2025-11-04
(hasEvent)	[Pathway:9851812] MLL3 and MLL4 regulate expression of PPARG target genes in hepatic steatosis_not ready for review_merged with adipogenesis [Homo sapiens]
(precedingEvent)	[BlackBoxEvent:9851871] MLL4-ASCOM,(MLL3-ASCOM) is recruited to PPARG2-bound regulatory elements of steatotic genes [Homo sapiens]
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No pathways have been reviewed or authored by Coactivators are recruited to liganded PPARG2:RXRA dimers (9851863)