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Details on Person p-Y78,Y102-PPARG2:RXRA binds regulatory elements of steatotic genes

Class:IdBlackBoxEvent:9851842
_displayNamep-Y78,Y102-PPARG2:RXRA binds regulatory elements of steatotic genes
_doReleaseFALSE
_timestamp2024-08-14 14:36:59
compartment[Compartment:7660] nucleoplasm
created[InstanceEdit:9851844] Orlic-Milacic, Marija, 2023-11-01
edited[InstanceEdit:9917569] Orlic-Milacic, Marija, 2024-08-07
input[Complex:9843268] p-Y78,Y102-PPARG2:RXRA Heterodimer [nucleoplasm] [Homo sapiens]
[DefinedSet:9851809] Steatotic target genes of PPARG and MLL3/4:nucleosomes [nucleoplasm] [Homo sapiens]
isChimericFALSE
modified[InstanceEdit:9857741] Orlic-Milacic, Marija, 2024-01-08
[InstanceEdit:9917569] Orlic-Milacic, Marija, 2024-08-07
[InstanceEdit:9917571] Orlic-Milacic, Marija, 2024-08-07
[InstanceEdit:9918134] Orlic-Milacic, Marija, 2024-08-14
namep-Y78,Y102-PPARG2:RXRA binds regulatory elements of steatotic genes
output[DefinedSet:9851843] p-Y78,Y102-PPARG2:RXRA heterodimer:steatotic target genes of PPARG and MLL3/4:nucleosome [nucleoplasm] [Homo sapiens]
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9851852] R-HSA-9851842.1
summation[Summation:9857740] Based on a mouse study, PPARG binds to regulatory elements o...
(hasEvent)[Pathway:9851812] MLL3 and MLL4 regulate expression of PPARG target genes in hepatic steatosis_not ready for review_merged with adipogenesis [Homo sapiens]
(precedingEvent)[BlackBoxEvent:9851841] Unliganded p-Y78,Y102-PPARG:RXRA heterodimer recruits corepressors to target gene loci [Homo sapiens]
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