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Details on Person Targeted inactivation of MLL3 histone H3-Lys-4 methyltransferase activity in the mouse reveals vital roles for MLL3 in adipogenesis

Class:IdLiteratureReference:9851793
_displayNameTargeted inactivation of MLL3 histone H3-Lys-4 methyltransferase activity in the mouse reveals vital roles for MLL3 in adipogenesis
_timestamp2023-10-31 12:07:38
author[Person:5244730] Lee, Jeongkyung
[Person:9851791] Saha, Pradip K
[Person:141858] Yang, QH
[Person:5244689] Lee, Seunghee
[Person:9851797] Park, Jung Yoon
[Person:9851792] Suh, Yousin
[Person:5244724] Lee, Soo-Kyung
[Person:9851794] Chan, Lawrence
[Person:3215148] Roeder, Robert G
[Person:5244758] Lee, Jae W
created[InstanceEdit:9851795] Orlic-Milacic, Marija, 2023-10-31
journalProc Natl Acad Sci U S A
pages19229-34
pubMedIdentifier19047629
titleTargeted inactivation of MLL3 histone H3-Lys-4 methyltransferase activity in the mouse reveals vital roles for MLL3 in adipogenesis
volume105
year2008
(literatureReference)[Summation:9843896] Expression of the FABP4 gene, encoding Fatty acid-binding pr...
[Summation:9856198] The MLL4-ASCOM complex (an MLL4 complex, composed of the cor...
[Summation:9856209] Transcription of the ADIPOQ gene, encoding a fat-derived hor...
[Summation:9856225] The KMT2D (MLL4)-ASCOM and KMT2C (MLL3)-ASCOM complexes meth...
[Pathway:9841922] MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis [Homo sapiens]
[BlackBoxEvent:9843904] Fabp4 gene transcription is stimulated by Pparg:Rxra and Mll4,(Mll3) complex [Mus musculus]
[Pathway:9851695] Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes [Homo sapiens]
[Pathway:9851812] MLL3 and MLL4 regulate expression of PPARG target genes in hepatic steatosis_not ready for review_merged with adipogenesis [Homo sapiens]
[Reaction:9856206] Mll4-ASCOM,(Mll3-ASCOM) complex is recruited to activated Pparg:Rxra complex at target adipogenic gene loci [Mus musculus]
[BlackBoxEvent:9856214] Adipoq gene expression is stimulated by Pparg and Mll4,(Mll3) complex [Mus musculus]
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