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Details on Person Rothfels, Karen, 2023-10-14

Class:Id	InstanceEdit:9851215
_displayName	Rothfels, Karen, 2023-10-14
_timestamp	2023-10-14 19:29:05
author	[Person:1226097] Rothfels, Karen
dateTime	2023-10-14 19:29:03
(authored)	[Pathway:9842640] Signaling by LTK in cancer [Homo sapiens] [Reaction:9842641] Active LTK receptor binds SHC1 [Homo sapiens] [Reaction:9842648] Autophosphorylation of LTK dimer:ALKAL1,2 [Homo sapiens] [Reaction:9842649] Active LTK receptor binds PI3K [Homo sapiens] [Reaction:9842651] Active LTK receptor phosphorylates SHC1 [Homo sapiens] [Reaction:9842655] IRS1 recruits GRB2 to active LTK [Homo sapiens] [Reaction:9842659] CLIP1(1-1083)-LTK(488-864) fusion dimerizes [Homo sapiens] [Reaction:9842660] LTK binds ALKAL ligand [Homo sapiens] [Pathway:9842663] Signaling by LTK [Homo sapiens] [BlackBoxEvent:9842665] Active LTK binds GRB2:TNK2 [Homo sapiens] List all 16 refering instances
(edited)	[Pathway:9842640] Signaling by LTK in cancer [Homo sapiens] [Reaction:9842641] Active LTK receptor binds SHC1 [Homo sapiens] [Reaction:9842648] Autophosphorylation of LTK dimer:ALKAL1,2 [Homo sapiens] [Reaction:9842649] Active LTK receptor binds PI3K [Homo sapiens] [Reaction:9842651] Active LTK receptor phosphorylates SHC1 [Homo sapiens] [Reaction:9842655] IRS1 recruits GRB2 to active LTK [Homo sapiens] [Reaction:9842656] ALK binds ALKAL ligand [Homo sapiens] [Reaction:9842659] CLIP1(1-1083)-LTK(488-864) fusion dimerizes [Homo sapiens] [Reaction:9842660] LTK binds ALKAL ligand [Homo sapiens] [Pathway:9842663] Signaling by LTK [Homo sapiens] List all 53 refering instances
(modified)	[Reaction:9700179] Ligand-independent dimerization of ALK fusions [Homo sapiens] [Reaction:9700184] Ligand-independent dimerization of point mutants of ALK [Homo sapiens] [Summation:9700657] Aberrant signaling by activated forms of ALK can be inhibite... [Summation:9711763] FRS proteins are phosphorylated downstream of ALK fusions in... [Summation:9711766] NPM-ALK binds to FRS2 and FRS3 as assessed by co-immunopreci... [Summation:9713418] The following ALK mutants and fusion proteins are sensitive ... [Summation:9723306] In addition to activation by translocations that lead to the... [Summation:9724088] MYH9 and RNF213 are unusual fusion partners of ALK that have... [Summation:9724127] Various ALK fusions and point mutants have been shown to for... [Summation:9725537] ALK is activated in a range of cancers as a result of amplif... List all 13 refering instances
(structureModified)	[Reaction:9842656] ALK binds ALKAL ligand [Homo sapiens]
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No pathways have been reviewed or authored by Rothfels, Karen, 2023-10-14 (9851215)