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Details on Person Crizotinib-driven IL10RA gene expression in NPM1-ALK

Class:IdBlackBoxEvent:9851068
_displayNameCrizotinib-driven IL10RA gene expression in NPM1-ALK
_doReleaseTRUE
_timestamp2023-11-08 15:59:37
authored[InstanceEdit:9851210] Rothfels, Karen, 2023-10-14
compartment[Compartment:7660] nucleoplasm
[Compartment:876] plasma membrane
created[InstanceEdit:9851067] Rothfels, Karen, 2023-10-12
disease[Disease:9699595] anaplastic large cell lymphoma
[Disease:1500689] cancer
edited[InstanceEdit:9851215] Rothfels, Karen, 2023-10-14
input[EntityWithAccessionedSequence:9850859] IL10RA gene [nucleoplasm] [Homo sapiens]
isChimericFALSE
literatureReference[LiteratureReference:9843025] IL10RA modulates crizotinib sensitivity in NPM1-ALK+ anaplastic large cell lymphoma
modified[InstanceEdit:9851737] Rothfels, Karen, 2023-10-30
[InstanceEdit:9852941] Rothfels, Karen, 2023-11-08
[InstanceEdit:9852942] Rothfels, Karen, 2023-11-08
nameCrizotinib-driven IL10RA gene expression in NPM1-ALK
output[EntityWithAccessionedSequence:449841] IL10RA [plasma membrane] [Homo sapiens]
precedingEvent
regulatedBy[PositiveGeneExpressionRegulation:9850987] Positive gene expression regulation by 'crizotinib:NPM1-ALK fusion dimer [cytosol]'
regulationReference[RegulationReference:9851035] Positive gene expression regulation by 'crizotinib:NPL1-ALK fusion dimer [cytosol]' IL10RA modulates crizotinib sensitivity in NPM1-ALK+ anaplastic large cell lymphoma
releaseDate2023-12-06
reviewed[InstanceEdit:9852935] Turner, Suzanne, 2023-11-08
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9851069] R-HSA-9851068.1
summation[Summation:9850811] Expression of IL10RA is upregulated in NPM1-ALK cells treate...
(hasEvent)[Pathway:9725371] Nuclear events stimulated by ALK signaling in cancer [Homo sapiens]
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No pathways have been reviewed or authored by Crizotinib-driven IL10RA gene expression in NPM1-ALK (9851068)
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