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Details on Person Diagram of Ion channel transport
| Class:Id | PathwayDiagram:984845 |
|---|---|
| _displayName | Diagram of Ion channel transport |
| _timestamp | 2026-03-02 18:25:42 |
| created | [InstanceEdit:984846] Jassal, B, 2010-11-03 |
| height | 1764 |
| modified | [InstanceEdit:984847] Jassal, B, 2010-11-03 [InstanceEdit:1369074] Jassal, B, 2011-07-04 [InstanceEdit:1679285] Matthews, L, 2011-10-19 [InstanceEdit:1824279] Jassal, B, 2011-10-26 [InstanceEdit:1825536] Jassal, B, 2011-10-26 [InstanceEdit:1826781] Jassal, B, 2011-10-26 [InstanceEdit:2010558] Matthews, L, 2011-11-22 [InstanceEdit:2867914] Jassal, Bijay, 2012-12-19 [InstanceEdit:2867962] Jassal, Bijay, 2012-12-20 [InstanceEdit:2892455] Jassal, Bijay, 2013-01-02 [InstanceEdit:2892459] Jassal, B, 2013-01-02 [InstanceEdit:2895789] Jassal, B, 2013-01-03 [InstanceEdit:3000513] Jassal, Bijay, 2013-01-28 [InstanceEdit:3132751] Jassal, Bijay, 2013-02-13 [InstanceEdit:3769477] Jassal, B, 2013-06-24 [InstanceEdit:3907280] Gillespie, ME, 2013-07-18 [InstanceEdit:4420234] Jassal, B, 2013-08-30 [InstanceEdit:5348848] Jassal, Bijay, 2014-03-20 [InstanceEdit:5357399] Jassal, Bijay, 2014-03-20 [InstanceEdit:5357401] Jassal, Bijay, 2014-03-20 [InstanceEdit:5357421] Jassal, Bijay, 2014-03-21 [InstanceEdit:5357507] Jassal, Bijay, 2014-03-21 [InstanceEdit:5358766] Jassal, Bijay, 2014-04-03 [InstanceEdit:5358988] Jassal, Bijay, 2014-04-07 [InstanceEdit:5358993] Jassal, Bijay, 2014-04-07 [InstanceEdit:5358998] Jassal, Bijay, 2014-04-07 [InstanceEdit:5362700] Jassal, Bijay, 2014-04-17 [InstanceEdit:5624215] Jassal, Bijay, 2014-09-22 [InstanceEdit:5671713] Jassal, Bijay, 2015-02-02 [InstanceEdit:5673780] Jassal, Bijay, 2015-02-10 [InstanceEdit:6784605] Jassal, Bijay, 2015-06-22 [InstanceEdit:6792750] Jassal, Bijay, 2015-08-27 [InstanceEdit:6792760] Jassal, Bijay, 2015-08-27 [InstanceEdit:6792766] Jassal, Bijay, 2015-08-27 [InstanceEdit:6792777] Jassal, Bijay, 2015-08-27 [InstanceEdit:8855180] Wu, G, 2016-02-02 [InstanceEdit:8863516] Jupe, Steve, 2016-03-08 [InstanceEdit:8863579] Jupe, Steve, 2016-03-09 [InstanceEdit:8951843] Jassal, Bijay, 2016-12-12 [InstanceEdit:8951844] Jassal, Bijay, 2016-12-12 [InstanceEdit:8981152] Jassal, Bijay, 2017-03-02 [InstanceEdit:8981155] Jassal, Bijay, 2017-03-02 [InstanceEdit:9007331] Jassal, Bijay, 2017-05-30 [InstanceEdit:9016832] Jassal, Bijay, 2017-08-16 [InstanceEdit:9650176] Jassal, Bijay, 2019-06-20 [InstanceEdit:9659588] Jassal, Bijay, 2019-08-29 [InstanceEdit:9659619] Jassal, Bijay, 2019-08-29 [InstanceEdit:9670768] Jassal, Bijay, 2019-12-16 [InstanceEdit:9690425] Jassal, Bijay, 2020-06-01 [InstanceEdit:9690589] Jassal, Bijay, 2020-06-03 [InstanceEdit:9701181] Jassal, Bijay, 2020-09-24 [InstanceEdit:9701189] Jassal, Bijay, 2020-09-24 [InstanceEdit:9701226] Jassal, Bijay, 2020-09-25 [InstanceEdit:9701254] Jassal, Bijay, 2020-09-25 [InstanceEdit:9727196] Jassal, Bijay, 2021-04-15 [InstanceEdit:9727238] Jassal, Bijay, 2021-04-15 [InstanceEdit:9764689] May, Bruce, 2022-02-13 [InstanceEdit:9764690] May, Bruce, 2022-02-13 [InstanceEdit:9774550] D'Eustachio, Peter, 2022-05-25 [InstanceEdit:9815410] D'Eustachio, Peter, 2022-08-17 [InstanceEdit:9962911] D'Eustachio, Peter, 2025-08-11 [InstanceEdit:9970137] Stephan, Ralf, 2025-10-28 [InstanceEdit:9970138] Stephan, Ralf, 2025-10-28 [InstanceEdit:9970139] Stephan, Ralf, 2025-10-28 [InstanceEdit:9983790] Matthews, Lisa, 2026-02-27 [InstanceEdit:9984013] Matthews, Lisa, 2026-03-02 |
| representedPathway | [Pathway:983712] Ion channel transport [Homo sapiens] |
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255" hideComponents="true"> <Properties> <displayName>CUTC:4xCu+</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableChemical id="3632" reactomeId="947590" position="371 1039" bounds="358 1024 27 30" textPosition="362 1028" /> <org.gk.render.RenderableChemical id="3633" reactomeId="29370" position="317 1042" bounds="297 1027 41 30" textPosition="301 1031" /> <org.gk.render.RenderableComplex id="3634" reactomeId="5357794" position="2301 1504" bounds="2234 1480 135 48" textPosition="2237 1478" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>p-S-RIPK1:p-S199,227-RIPK3:p-T357,S358-MLKL oligomer</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableChemical id="3636" reactomeId="29418" position="2392 1109" bounds="2366 1094 52 30" textPosition="2370 1098"> <Properties> <displayName>Mn2+</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableChemical id="3637" reactomeId="29356" position="2450 1106" bounds="2429 1091 43 30" textPosition="2433 1095" /> <org.gk.render.RenderableChemical id="3638" reactomeId="113592" position="2504 1105" bounds="2484 1090 40 30" textPosition="2488 1094"> <Properties> <displayName>ATP</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableChemical id="3639" reactomeId="1981162" position="2388 942" bounds="2362 927 52 30" textPosition="2366 931" /> <org.gk.render.RenderableChemical id="3640" reactomeId="29370" position="2538 929" bounds="2518 914 41 30" textPosition="2522 918"> <Properties> <displayName>ADP</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableProtein id="3641" reactomeId="939749" position="2497 991" bounds="2465 980 64 22" textPosition="2465 980"> <Properties> <displayName>ATP13A1</displayName> </Properties> </org.gk.render.RenderableProtein> <org.gk.render.RenderableChemical id="3643" reactomeId="29372" position="2518 898" bounds="2505 883 27 30" textPosition="2509 887" /> <org.gk.render.RenderableChemical id="3646" reactomeId="5692450" position="646 1025" bounds="621 1010 51 30" textPosition="625 1014"> <Properties> <displayName>cation</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableChemical id="3647" reactomeId="5692484" position="731 1162" bounds="706 1147 51 30" textPosition="710 1151" /> <org.gk.render.RenderableProtein id="3648" reactomeId="939762" position="766 1091" bounds="734 1080 64 22" textPosition="734 1080"> <Properties> <displayName>ATP13A2</displayName> </Properties> </org.gk.render.RenderableProtein> <org.gk.render.RenderableChemical id="3670" reactomeId="29356" position="684 983" bounds="663 968 43 30" textPosition="667 972" /> <org.gk.render.RenderableChemical id="3671" reactomeId="113592" position="731 1022" bounds="711 1007 40 30" textPosition="715 1011" /> <org.gk.render.RenderableChemical id="3690" reactomeId="29370" position="617 1126" bounds="597 1111 41 30" textPosition="601 1115" /> <org.gk.render.RenderableChemical id="3692" reactomeId="29372" position="634 1183" bounds="621 1168 27 30" textPosition="625 1172" /> <org.gk.render.RenderableComplex id="3693" reactomeId="444601" position="2321 718" bounds="2262 700 119 36" textPosition="2262 700" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>CAMK2 heteromer:CALM:4xCa2+</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableProtein id="3694" reactomeId="5215917" position="2358 754" bounds="2343 743 30 22" textPosition="2343 743"> <Properties> <displayName>SLN</displayName> </Properties> </org.gk.render.RenderableProtein> <org.gk.render.RenderableEntitySet id="3748" reactomeId="8863527" position="2051 393" bounds="2019 377 64 32" textPosition="2019 375"> <Properties> <displayName>STOML3, (STOM)</displayName> </Properties> </org.gk.render.RenderableEntitySet> <org.gk.render.RenderableComplex id="3749" reactomeId="8863519" position="1927 387" bounds="1883 363 88 48" textPosition="1886 361" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>ASIC trimers:H+:STOML3,(STOM)</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableProtein id="3755" reactomeId="936912" position="1498 723" bounds="1474 712 48 22" textPosition="1475 712"> <Properties> <displayName>ATP7B</displayName> </Properties> </org.gk.render.RenderableProtein> <org.gk.render.RenderableChemical id="3813" reactomeId="74126" position="403 338" bounds="386 323 35 30" textPosition="390 327" /> <org.gk.render.RenderableProtein id="3817" reactomeId="5215981" position="1376 904" bounds="1345 893 63 22" textPosition="1345 893"> <Properties> <displayName>ATP6AP1</displayName> </Properties> </org.gk.render.RenderableProtein> <org.gk.render.RenderableComplex id="3818" reactomeId="912600" position="1450 902" bounds="1417 891 67 22" textPosition="1417 891" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>V-ATPase</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableComplex id="3819" reactomeId="5252081" position="1608 902" bounds="1546 891 125 22" textPosition="1546 891" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>V-ATPase:ATP6AP1</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableProtein id="3820" reactomeId="9016707" position="2363 1182" bounds="2338 1171 50 22" textPosition="2339 1171"> <Properties> <displayName>CALM1</displayName> </Properties> </org.gk.render.RenderableProtein> <org.gk.render.RenderableChemical id="3924" reactomeId="74113" position="166 856" bounds="145 841 43 30" textPosition="149 845"> <Properties> <displayName>Na+</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableChemical id="3926" reactomeId="83910" position="340 856" bounds="319 841 43 30" textPosition="323 845" /> 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id="3958" reactomeId="9649955" position="2167 395" bounds="2122 371 90 49" textPosition="2121 370" bgColor="184 154 230" fgColor="161 1 2" isForDrug="true" hideComponents="true"> <Properties> <displayName>ASIC3 trimer:ASIC3 channel blockers</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableProtein id="4106" reactomeId="2684927" position="3022 440" bounds="3000 429 45 23" textPosition="3001 429"> <Properties> <displayName>ANO1</displayName> </Properties> </org.gk.render.RenderableProtein> <org.gk.render.RenderableEntitySet id="4122" reactomeId="9659575" position="3039 330" bounds="3006 314 66 32" textPosition="3008 312" bgColor="184 154 230" fgColor="161 1 2" lineColor="255 0 0" isForDrug="true" isForDisease="true"> <Properties> <displayName>ANO1 inhibitors</displayName> </Properties> </org.gk.render.RenderableEntitySet> <org.gk.render.RenderableComplex id="4123" reactomeId="9659597" position="2913 390" bounds="2869 371 88 38" textPosition="2871 373" bgColor="184 154 230" fgColor="161 1 2" isForDrug="true" hideComponents="true"> <Properties> <displayName>ANO1:ANO1 inhibitors</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableChemical id="4124" reactomeId="29356" position="345 510" bounds="324 495 43 30" textPosition="328 499" /> <org.gk.render.RenderableChemical id="4125" reactomeId="113592" position="349 546" bounds="329 531 40 30" textPosition="333 535" /> <org.gk.render.RenderableChemical id="4128" reactomeId="74016" position="280 479" bounds="255 464 50 30" textPosition="259 468" /> <org.gk.render.RenderableChemical id="4160" reactomeId="2672383" position="2564 325" bounds="2538 310 52 30" textPosition="2542 314"> <Properties> <displayName>NSAID</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableEntitySet id="4185" reactomeId="9684063" position="543 221" bounds="497 204 92 35" textPosition="509 204" bgColor="184 154 230" fgColor="161 1 2" isForDrug="true"> <Properties> <displayName>cardiac glycosides</displayName> </Properties> </org.gk.render.RenderableEntitySet> <org.gk.render.RenderableComplex id="4186" reactomeId="9684072" position="470 392" bounds="423 368 94 49" textPosition="423 367" bgColor="184 154 230" fgColor="161 1 2" isForDrug="true" hideComponents="true"> <Properties> <displayName>ATP1A:ATP1B:FXYD:cardiac glycosides</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableChemicalDrug id="4189" reactomeId="2672379" position="2723 317" bounds="2688 302 71 30" textPosition="2692 306" bgColor="184 154 230" fgColor="161 1 2" lineColor="255 0 0" isForDisease="true"> <Properties> <displayName>amiloride</displayName> </Properties> </org.gk.render.RenderableChemicalDrug> <org.gk.render.RenderableChemicalDrug id="4190" reactomeId="2672379" position="169 779" bounds="134 764 71 30" textPosition="138 768" bgColor="184 154 230" fgColor="161 1 2" lineColor="255 0 0" isForDisease="true" /> <org.gk.render.RenderableChemical id="4222" reactomeId="74016" position="2651 1530" bounds="2626 1515 50 30" textPosition="2630 1519" /> <org.gk.render.RenderableChemical id="4224" reactomeId="74112" position="2667 1711" bounds="2642 1696 50 30" textPosition="2646 1700" /> <org.gk.render.RenderableEntitySet id="4288" reactomeId="9701105" position="3005 1703" bounds="2972 1687 66 32" textPosition="2977 1685" bgColor="184 154 230" fgColor="161 1 2" isForDrug="true"> <Properties> <displayName>TRPV1 agonists</displayName> </Properties> </org.gk.render.RenderableEntitySet> <org.gk.render.RenderableComplex id="4289" reactomeId="9701107" position="2915 1637" bounds="2858 1620 114 35" textPosition="2868 1619" bgColor="184 154 230" fgColor="161 1 2" isForDrug="true" hideComponents="true"> <Properties> <displayName>TRPV1:TRPV1 agonists</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableComplex id="4391" reactomeId="9701182" position="2493 1638" bounds="2460 1620 66 36" textPosition="2464 1620" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>TRPA1 tetramer</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableProtein id="4453" reactomeId="2671938" position="2790 1636" bounds="2766 1625 48 22" textPosition="2766 1625"> <Properties> <displayName>TRPV1</displayName> </Properties> </org.gk.render.RenderableProtein> <org.gk.render.RenderableEntitySet id="4511" reactomeId="9701157" position="3121 1586" bounds="3084 1570 75 33" textPosition="3093 1569" bgColor="184 154 230" fgColor="161 1 2" isForDrug="true"> <Properties> <displayName>TRPV1 blockers</displayName> </Properties> </org.gk.render.RenderableEntitySet> <org.gk.render.RenderableComplex id="4512" reactomeId="9701146" position="3019 1472" bounds="2973 1453 93 38" textPosition="2973 1455" bgColor="184 154 230" fgColor="161 1 2" isForDrug="true" hideComponents="true"> <Properties> <displayName>TRPV1:TRPV1 blockers</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableEntitySet id="4559" reactomeId="9701208" position="2455 1745" bounds="2397 1734 117 22" textPosition="2397 1734" bgColor="184 154 230" fgColor="161 1 2" isForDrug="true"> <Properties> <displayName>TRPA1 antagonists</displayName> </Properties> </org.gk.render.RenderableEntitySet> <org.gk.render.RenderableComplex id="4560" reactomeId="9701210" position="2379 1638" bounds="2321 1620 117 36" textPosition="2321 1620" bgColor="184 154 230" fgColor="161 1 2" isForDrug="true" hideComponents="true"> <Properties> <displayName>TRPA1 tetramer:TRPA1 antagonists</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableChemical id="4617" reactomeId="113592" position="1243 491" bounds="1223 476 40 31" textPosition="1227 480" /> <org.gk.render.RenderableChemical id="4618" reactomeId="29356" position="1245 452" bounds="1224 437 43 31" textPosition="1228 441"> <Properties> <displayName>H2O</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableChemical id="4619" reactomeId="29370" position="1028 441" bounds="1008 426 41 31" textPosition="1012 430" /> <org.gk.render.RenderableComplex id="4620" reactomeId="9727185" position="1142 393" bounds="1097 382 90 23" textPosition="1097 383" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>ATP4A:ATP4B</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableChemical id="4622" reactomeId="351626" position="1082 350" bounds="1064 335 36 30" textPosition="1068 339" /> <org.gk.render.RenderableChemical id="4624" reactomeId="29372" position="1033 481" bounds="1017 468 33 27" textPosition="1024 470" /> <org.gk.render.RenderableChemical id="4626" reactomeId="70106" position="1198 530" bounds="1180 515 36 30" textPosition="1184 519" /> <org.gk.render.RenderableChemical id="4628" reactomeId="29804" position="1082 565" bounds="1065 550 35 30" textPosition="1069 554" /> <org.gk.render.RenderableChemical id="4630" reactomeId="74126" position="1197 345" bounds="1180 330 35 30" textPosition="1184 334" /> <org.gk.render.RenderableComplex id="4634" reactomeId="9727197" position="1303 393" bounds="1256 375 94 36" textPosition="1258 375" bgColor="184 154 230" fgColor="161 1 2" isForDrug="true" hideComponents="true"> <Properties> <displayName>ATP4AATP4B:PPIs</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableEntitySet id="4772" reactomeId="9727189" position="1184 250" bounds="1163 238 43 24" textPosition="1169 239" bgColor="184 154 230" fgColor="161 1 2" isForDrug="true"> <Properties> <displayName>PPIs</displayName> </Properties> </org.gk.render.RenderableEntitySet> <org.gk.render.RenderableChemical id="4774" reactomeId="113592" position="364 907" bounds="344 892 40 30" textPosition="348 896" /> <org.gk.render.RenderableChemical id="4786" reactomeId="2889072" position="1434 1187" bounds="1413 1172 43 31" textPosition="1417 1176" /> <org.gk.render.RenderableChemical id="4787" reactomeId="2889083" position="1606 1312" bounds="1585 1297 43 31" textPosition="1589 1301" /> <org.gk.render.RenderableComplex id="4795" reactomeId="9774552" position="1511 1232" bounds="1478 1213 66 38" textPosition="1483 1215" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>SLC9B2 dimer</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableChemical id="4799" reactomeId="2889057" position="1391 1209" bounds="1373 1194 36 31" textPosition="1377 1198"> <Properties> <displayName>Li+</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableChemical id="4800" reactomeId="2889068" position="1607 1357" bounds="1589 1342 36 31" textPosition="1593 1346" /> <org.gk.render.RenderableChemical id="4801" reactomeId="29356" position="1734 757" bounds="1714 742 40 31" textPosition="1717 746" /> <org.gk.render.RenderableChemical id="4802" reactomeId="113592" position="1685 761" bounds="1665 746 40 31" textPosition="1669 750" /> <org.gk.render.RenderableChemical id="4803" reactomeId="29370" position="1545 795" bounds="1525 780 40 31" textPosition="1529 784" /> <org.gk.render.RenderableChemical id="4804" reactomeId="9970129" position="1633 675" bounds="1616 660 35 31" textPosition="1618 658" /> <org.gk.render.RenderableChemical id="4806" reactomeId="3299744" position="1634 778" bounds="1617 763 34 30" textPosition="1618 760" /> <org.gk.render.RenderableChemical id="4808" reactomeId="70106" position="1567 753" bounds="1555 742 24 23" textPosition="1558 736" /> <org.gk.render.RenderableChemical id="4811" reactomeId="29372" position="1586 793" bounds="1573 778 27 30" textPosition="1577 782" /> <org.gk.render.RenderableChemical id="4825" reactomeId="3299744" position="1637 510" bounds="1620 495 34 30" textPosition="1621 492" /> <org.gk.render.RenderableChemical id="4838" reactomeId="70106" position="1716 508" bounds="1704 497 24 23" textPosition="1707 491" /> <org.gk.render.RenderableChemical id="4841" reactomeId="9970133" position="1550 340" bounds="1528 325 45 31" textPosition="1530 329" /> <org.gk.render.RenderableComplex id="4842" reactomeId="9961464" position="3028 473" bounds="2988 462 81 23" textPosition="2988 463" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>ANO1 dimer</displayName> </Properties> </org.gk.render.RenderableComplex> </Nodes> <Edges> <org.gk.render.RenderableReaction id="2820" reactomeId="418309" points="2051 685, 1786 392, 1773 345" position="1786 392" lineWidth="1.0"> <Inputs> <Input id="86" /> </Inputs> <Outputs> <Output id="87" /> </Outputs> <Catalysts> <Catalyst id="88" points="1751 392" /> </Catalysts> <Properties> <displayName>ATP2B1-4 transport cytosolic Ca2+ to extracellular region</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="2821" reactomeId="418365" points="2305 599, 2343 599, 2366 600" position="2343 599" lineWidth="1.0"> <Inputs> <Input id="86" stoichiometry="2" points="2093 692" /> <Input id="89" stoichiometry="2" points="2283 582" /> </Inputs> <Outputs> <Output id="91" stoichiometry="2" points="2406 585" /> <Output id="90" stoichiometry="2" points="2417 652" /> </Outputs> <Catalysts> <Catalyst id="92" points="2342 621" /> </Catalysts> <Properties> <displayName>ATP2A1-3 transport cytosolic Ca2+ to dense tubular network lumen</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="2823" reactomeId="936883" points="1823 597, 1823 648, 1825 692" position="1823 648" lineWidth="1.0"> <Inputs> <Input id="86" points="2037 692" /> <Input id="98" points="1806 567" /> <Input id="99" points="1832 587" /> </Inputs> <Outputs> <Output id="101" points="1753 693" /> <Output id="102" points="1969 733" /> <Output id="100" points="1822 739" /> </Outputs> <Catalysts> <Catalyst id="103" points="1798 648" /> </Catalysts> <Properties> <displayName>ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="2828" reactomeId="427910" points="2261 775, 2320 776, 2374 776" position="2320 776" lineWidth="1.0"> <Inputs> <Input id="86" stoichiometry="2" points="2093 712" /> <Input id="94" stoichiometry="2" points="2030 885" /> </Inputs> <Outputs> <Output id="95" stoichiometry="2" points="2428 879" /> <Output id="90" stoichiometry="2" points="2422 681" /> </Outputs> <Catalysts> <Catalyst id="96" points="2360 839" /> </Catalysts> <Inhibitors> <Inhibitor id="3495" points="2190 845" /> <Inhibitor id="3694" points="2340 762" /> </Inhibitors> <Activators> <Activator id="3494" points="2272 838" /> <Activator id="3693" points="2320 739" /> <Activator id="3496" points="2311 1145" /> </Activators> <Properties> <displayName>ATP2A1-3 transport Ca2+ from cytosol to ER lumen</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="2830" reactomeId="936897" points="402 475, 564 475, 620 475" position="564 475" lineWidth="1.0"> <Inputs> <Input id="4124" points="370 496" /> <Input id="105" stoichiometry="3" points="402 552" /> <Input id="4125" points="360 528" /> <Input id="3813" stoichiometry="2" points="402 356" /> </Inputs> <Outputs> <Output id="109" stoichiometry="3" points="620 348" /> <Output id="110" stoichiometry="2" points="661 585" /> <Output id="108" points="649 482" /> <Output id="111" points="654 510" /> </Outputs> <Catalysts> <Catalyst id="112" points="564 422" /> </Catalysts> <Inhibitors> <Inhibitor id="4186" points="497 420" /> </Inhibitors> <Properties> <displayName>ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="2835" reactomeId="937311" points="842 461, 789 461, 725 461" position="789 461" lineWidth="1.0"> <Inputs> <Input id="2836" points="891 476" /> <Input id="104" points="842 362" /> <Input id="119" points="842 546" /> <Input id="2837" points="858 480" /> </Inputs> <Outputs> <Output id="110" points="673 585" /> <Output id="108" points="682 479" /> <Output id="111" points="680 510" /> <Output id="2841" points="725 366" /> </Outputs> <Catalysts> <Catalyst id="118" points="788 418" /> </Catalysts> <Properties> <displayName>ATP12A:ATP4B exchanges K+ for H+</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="2843" reactomeId="939763" points="1304 1579, 1269 1579, 1222 1579" position="1269 1579" lineWidth="1.0"> <Inputs> <Input id="120" points="1511 1636" /> <Input id="1135" points="1354 1544" /> <Input id="1137" points="1354 1579" /> </Inputs> <Outputs> <Output id="125" points="1171 1618" /> <Output id="1139" points="1174 1578" /> <Output id="1141" points="1187 1556" /> </Outputs> <Catalysts> <Catalyst id="126" points="1268 1616" /> </Catalysts> <Properties> <displayName>P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="2849" reactomeId="947591" points="1439 1578, 1463 1578, 1491 1578" position="1463 1578" lineWidth="1.0"> <Inputs> <Input id="125" points="1175 1652, 1206 1667, 1402 1667" /> <Input id="1135" points="1397 1549" /> <Input id="1137" points="1400 1578" /> </Inputs> <Outputs> <Output id="120" points="1528 1625" /> <Output id="1102" points="1509 1551" /> <Output id="1064" points="1528 1577" /> </Outputs> <Catalysts> <Catalyst id="126" points="1348 1636, 1462 1640" /> </Catalysts> <Properties> <displayName>P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="2861" reactomeId="2671885" points="2634 342, 2634 393, 2634 441" position="2634 393" lineWidth="1.0"> <Inputs> <Input id="2261" /> </Inputs> <Outputs> <Output id="2247" /> </Outputs> <Catalysts> <Catalyst id="2242" points="2581 392" /> </Catalysts> <Inhibitors> <Inhibitor id="2245" points="2685 393" /> <Inhibitor id="4160" points="2579 343" /> <Inhibitor id="4189" points="2705 335" /> </Inhibitors> <Properties> <displayName>ASIC trimers:H+ transport extracellular Na+ to cytosol</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="2862" reactomeId="2672334" points="191 855, 244 855, 316 855" position="244 855" lineWidth="1.0"> <Inputs> <Input id="3924" /> </Inputs> <Outputs> <Output id="3926" /> </Outputs> <Catalysts> <Catalyst id="2275" points="244 909" /> </Catalysts> <Inhibitors> <Inhibitor id="4190" points="183 797" /> </Inhibitors> <Properties> <displayName>SCNN channels transport extracellular Na+ to cytosol</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="2864" reactomeId="2682349" points="265 954, 278 972, 278 997" position="278 972" lineWidth="1.0"> <Inputs> <Input id="2275" points="251 937" /> <Input id="4774" points="341 916" /> <Input id="2278" stoichiometry="6" points="403 929" /> </Inputs> <Outputs> <Output id="3632" points="355 1032" /> <Output id="3633" points="304 1024" /> <Output id="2279" points="248 1060" /> </Outputs> <Catalysts> <Catalyst id="2282" points="364 971" /> </Catalysts> <Activators> <Activator id="2283" points="416 1017" /> </Activators> <Properties> <displayName>RAF1:SGK:TSC22D3:WPP ubiquitinates SCNN channels</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="2867" reactomeId="2684901" points="2782 708, 3019 612, 3151 703" position="3019 612" lineWidth="1.0"> <Inputs> <Input id="2311" /> </Inputs> <Outputs> <Output id="2313" /> </Outputs> <Catalysts> <Catalyst id="2309" points="3019 572" /> </Catalysts> <Activators> <Activator id="2327" points="2876 566" /> <Activator id="2902" points="2984 836, 2845 771" /> </Activators> <Properties> <displayName>ANOs transport cytosolic Cl- to extracellular region</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="2869" reactomeId="2744349" points="2782 714, 3020 714, 3151 714" position="3020 714" lineWidth="1.0"> <Inputs> <Input id="2311" /> </Inputs> <Outputs> <Output id="2313" /> </Outputs> <Catalysts> <Catalyst id="2557" points="3019 735" /> </Catalysts> <Properties> <displayName>TTYH1 transports cytosolic Cl- to extracellular region</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="2871" reactomeId="2744242" points="2782 719, 3019 779, 3151 722" position="3019 779" lineWidth="1.0"> <Inputs> <Input id="2311" /> </Inputs> <Outputs> <Output id="2313" /> </Outputs> <Catalysts> <Catalyst id="2452" points="3021 801" /> </Catalysts> <Activators> <Activator id="2454" points="2783 836" /> <Activator id="2902" points="2979 836, 2936 824, 2936 778" /> </Activators> <Properties> <displayName>TTYH2/3 transport cytosolic Cl- to extracellular region</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="2873" reactomeId="2744228" points="2782 710, 3018 644, 3151 706" position="3018 644" lineWidth="1.0"> <Inputs> <Input id="2311" /> </Inputs> <Outputs> <Output id="2313" /> </Outputs> <Catalysts> <Catalyst id="2373" points="3019 671" /> </Catalysts> <Properties> <displayName>CLCN1/2/KA/KB transport cytosolic Cl- to extracellular region</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="2875" reactomeId="2744361" points="2774 733, 2926 894, 3019 894, 3091 894, 3164 733" position="3019 894" lineWidth="1.0"> <Inputs> <Input id="2311" /> </Inputs> <Outputs> <Output id="2313" /> </Outputs> <Catalysts> <Catalyst id="2468" points="3019 936" /> </Catalysts> <Activators> <Activator id="2454" points="2783 846" /> <Activator id="2902" points="3009 870" /> </Activators> <Properties> <displayName>BESTs transport cytosolic Cl- to extracellular region</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="2877" reactomeId="2752067" points="2994 998, 3020 998, 3071 998" position="3020 998" lineWidth="1.0"> <Inputs> <Input id="2498" /> </Inputs> <Outputs> <Output id="2499" /> </Outputs> <Catalysts> <Catalyst id="2468" points="3020 970" /> </Catalysts> <Properties> <displayName>BESTs transport cytosolic HCO3- to extracellular region</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="2878" reactomeId="2685505" points="727 1250, 727 1285, 727 1322" position="727 1285" lineWidth="1.0"> <Inputs> <Input id="1474" /> </Inputs> <Outputs> <Output id="1478" /> </Outputs> <Catalysts> <Catalyst id="1475" points="783 1285" /> </Catalysts> <Activators> <Activator id="1476" points="649 1285" /> </Activators> <Properties> <displayName>TPCN1/2 transport lysosomal Ca2+ to cytosol</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="2879" reactomeId="2730664" points="329 349, 329 389, 329 430" position="329 389" lineWidth="1.0"> <Inputs> <Input id="2359" /> </Inputs> <Outputs> <Output id="2357" /> </Outputs> <Catalysts> <Catalyst id="2353" points="287 389" /> </Catalysts> <Inhibitors> <Inhibitor id="4128" points="288 461" /> </Inhibitors> <Properties> <displayName>UNC79:UNC80:NALCN transports Na+ extracellular region to cytosol</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="2881" reactomeId="2731002" points="1136 828, 1136 849, 1136 870" position="1136 849" lineWidth="1.0"> <Inputs> <Input id="1410" points="1118 817" /> <Input id="1414" points="1181 807" /> </Inputs> <Outputs> <Output id="1411" points="1118 885" /> <Output id="1416" points="1209 892" /> </Outputs> <Catalysts> <Catalyst id="1412" points="1160 847" /> </Catalysts> <Properties> <displayName>CLCN3 exchanges Cl- for H+</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="2884" reactomeId="2730959" points="919 1222, 920 1195, 920 1168" position="920 1195" lineWidth="1.0"> <Inputs> <Input id="1600" points="901 1238" /> <Input id="1606" points="963 1314" /> </Inputs> <Outputs> <Output id="1601" points="900 1150" /> <Output id="1620" points="995 1115" /> </Outputs> <Catalysts> <Catalyst id="1602" points="952 1195" /> </Catalysts> <Properties> <displayName>CLCN7:OSTM1 exchanges Cl- for H+</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="2886" reactomeId="2855020" points="2272 1239, 2298 1241, 2366 1318" position="2298 1241" lineWidth="1.0"> <Inputs> <Input id="1931" /> </Inputs> <Outputs> <Output id="1936" /> </Outputs> <Catalysts> <Catalyst id="1932" points="2262 1261" /> </Catalysts> <Inhibitors> <Inhibitor id="1934" points="2296 1323" /> <Inhibitor id="3820" points="2350 1196" /> </Inhibitors> <Activators> <Activator id="1938" points="2354 1264" /> <Activator id="1933" points="2323 1241" /> <Activator id="3496" points="2309 1173" /> </Activators> <Properties> <displayName>RYR tetramers transport Ca2+ from sarcoplasmic reticulum lumen to cytosol</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="2892" reactomeId="2872497" points="2968 1165, 3020 1165, 3063 1165" position="3020 1165" lineWidth="1.0"> <Inputs> <Input id="2482" /> </Inputs> <Outputs> <Output id="2483" /> </Outputs> <Catalysts> <Catalyst id="2484" points="3020 1201" /> </Catalysts> <Properties> <displayName>SLC17A3-2 transports cytosolic urate to extracellular region</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="2894" reactomeId="2872444" points="1729 1587, 1750 1588, 1787 1586" position="1750 1588" lineWidth="1.0"> <Inputs> <Input id="2545" points="1684 1658" /> <Input id="2529" points="1713 1560" /> </Inputs> <Outputs> <Output id="2543" points="1813 1556" /> <Output id="2527" points="1815 1654" /> </Outputs> <Catalysts> <Catalyst id="2525" points="1750 1619" /> </Catalysts> <Properties> <displayName>SLC9B1/C2 exchange Na+ for H+</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="2896" reactomeId="2889070" points="1481 1286, 1528 1285, 1552 1286" position="1528 1285" lineWidth="1.0"> <Inputs> <Input id="4786" points="1441 1206" /> <Input id="2043" points="1459 1325" /> </Inputs> <Outputs> <Output id="2046" points="1596 1210" /> <Output id="4787" points="1582 1301" /> </Outputs> <Catalysts> <Catalyst id="4795" points="1517 1254" /> </Catalysts> <Properties> <displayName>SLC9B2 exchanges Na+ for H+</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="2898" reactomeId="2872463" points="1521 163, 1521 135, 1521 107" position="1521 135" lineWidth="1.0"> <Inputs> <Input id="2081" points="1461 163" /> <Input id="2085" points="1561 163" /> </Inputs> <Outputs> <Output id="2082" points="1452 107" /> <Output id="2087" points="1566 107" /> </Outputs> <Catalysts> <Catalyst id="2083" points="1387 135" /> </Catalysts> <Properties> <displayName>SLC9C1 exchanges Na+ for H+</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="2900" reactomeId="3295579" points="2224 1673, 2224 1639, 2224 1591" position="2224 1639" lineWidth="1.0"> <Inputs> <Input id="2764" /> </Inputs> <Outputs> <Output id="2762" /> </Outputs> <Catalysts> <Catalyst id="2759" points="2191 1638" /> </Catalysts> <Activators> <Activator id="3634" points="2287 1531" /> </Activators> <Properties> <displayName>TRPs transport extracellular Ca2+ to cytosol</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="2901" reactomeId="3295580" points="2041 1671, 2041 1637, 2041 1598" position="2041 1637" lineWidth="1.0"> <Inputs> <Input id="2770" /> </Inputs> <Outputs> <Output id="2768" /> </Outputs> <Catalysts> <Catalyst id="2766" points="2008 1636" /> </Catalysts> <Properties> <displayName>TRPM4,5 transport extracellular Na+ to cytosol</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="3008" reactomeId="5333671" points="2993 1110, 2873 1052, 2873 993" position="2873 1052" lineWidth="1.0"> <Inputs> <Input id="3009" /> </Inputs> <Outputs> <Output id="3010" points="3013 1039" /> <Output id="2902" points="2995 870" /> </Outputs> <Catalysts> <Catalyst id="3009" points="3004 1104, 2904 1041" /> </Catalysts> <Activators> <Activator id="2454" points="2763 860" /> </Activators> <Properties> <displayName>CLCAs self cleave</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="3162" reactomeId="5251989" points="904 1586, 859 1586, 830 1586" position="859 1586" lineWidth="1.0" reactionType="Omitted Process"> <Inputs> <Input id="3163" points="939 1589" /> <Input id="3164" points="953 1658" /> <Input id="3165" points="940 1562" /> </Inputs> <Outputs> <Output id="3166" points="781 1561" /> <Output id="3167" points="779 1517" /> <Output id="3170" points="776 1598" /> </Outputs> <Catalysts> <Catalyst id="3168" points="858 1620" /> </Catalysts> <Properties> <displayName>ATP13A4,5 transport divalent ions from extracellular region to cytosol</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="3265" reactomeId="5358977" points="1580 602, 1578 601, 1581 604" position="1578 601" lineWidth="1.0"> <Inputs> <Input id="4825" points="1627 528" /> <Input id="77" points="1540 526" /> <Input id="78" points="1581 527" /> </Inputs> <Outputs> <Output id="4804" points="1621 657" /> <Output id="79" points="1663 521" /> <Output id="81" points="1731 519" /> <Output id="4838" points="1701 516" /> </Outputs> <Catalysts> <Catalyst id="3491" points="1464 601" /> </Catalysts> <Properties> <displayName>ATP7A transports cytosolic Cu1+ to Golgi lumen</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="3320" reactomeId="5358976" points="1450 416, 1498 538, 1451 580" position="1498 538" lineWidth="1.0" reactionType="Omitted Process"> <Inputs> <Input id="3490" /> </Inputs> <Outputs> <Output id="3491" /> </Outputs> <Properties> <displayName>ATP7A:PDZD11 translocates from plasma membrane to TGN membrane</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="3321" reactomeId="5358981" points="1443 580, 1477 531, 1448 416" position="1477 531" lineWidth="1.0" reactionType="Omitted Process"> <Inputs> <Input id="3491" /> </Inputs> <Outputs> <Output id="3490" /> </Outputs> <Activators> <Activator id="3493" points="1456 535" /> </Activators> <Properties> <displayName>ATP7A:PDZD11 translocates from TGN membrane to plasma membrane</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="3626" reactomeId="5334788" points="1923 1341, 2020 1341" position="2020 1341" lineWidth="1.0" reactionType="Association"> <Inputs> <Input id="3627" points="1896 1312" /> <Input id="3628" stoichiometry="4" points="1900 1364" /> </Inputs> <Outputs> <Output id="3629" /> </Outputs> <Properties> <displayName>CUTC binds Cu+</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="3635" reactomeId="5692462" points="2440 1029, 2441 991, 2440 967" position="2441 991" lineWidth="1.0"> <Inputs> <Input id="3636" points="2401 1091" /> <Input id="3637" points="2448 1088" /> <Input id="3638" points="2491 1087" /> </Inputs> <Outputs> <Output id="3639" points="2417 954" /> <Output id="3640" points="2515 936" /> <Output id="3643" points="2502 909" /> </Outputs> <Catalysts> <Catalyst id="3641" points="2462 991" /> </Catalysts> <Properties> <displayName>ATP13A1 transports Mn2+ from cytosol to ER lumen</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="3645" reactomeId="5692480" points="678 1061, 678 1094, 678 1124" position="678 1094" lineWidth="1.0"> <Inputs> <Input id="3646" points="659 1043" /> <Input id="3670" points="682 1001" /> <Input id="3671" points="708 1036" /> </Inputs> <Outputs> <Output id="3690" points="641 1125" /> <Output id="3647" points="710 1144" /> <Output id="3692" points="645 1165" /> </Outputs> <Catalysts> <Catalyst id="3648" points="731 1092" /> </Catalysts> <Properties> <displayName>ATP13A2 transports cations from cytosol to lysosomal lumen</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="3747" reactomeId="8863494" points="2078 343, 2078 345, 1974 374" position="2078 345" lineWidth="1.0" reactionType="Association"> <Inputs> <Input id="3748" points="2059 371" /> <Input id="2242" points="2468 376, 2290 343" /> </Inputs> <Outputs> <Output id="3749" /> </Outputs> <Properties> <displayName>ASICs bind STOML3, (STOM)</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="3751" reactomeId="936895" points="1633 724, 1632 724, 1633 725" position="1632 724" lineWidth="1.0"> <Inputs> <Input id="4801" points="1711 750" /> <Input id="4802" points="1662 746" /> <Input id="4806" points="1633 760" /> </Inputs> <Outputs> <Output id="4803" points="1564 777" /> <Output id="4804" points="1633 694" /> <Output id="4808" points="1582 747" /> <Output id="4811" points="1596 775" /> </Outputs> <Catalysts> <Catalyst id="3755" points="1525 723" /> </Catalysts> <Properties> <displayName>ATP7B transports cytosolic Cu1+ to Golgi lumen</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="3757" reactomeId="2872498" points="2049 1066, 2049 1045, 2049 1019" position="2049 1045" lineWidth="1.0"> <Inputs> <Input id="2556" points="2034 1090" /> <Input id="1751" points="2067 1091" /> </Inputs> <Outputs> <Output id="1747" points="2032 1002" /> <Output id="2546" points="2065 1002" /> </Outputs> <Catalysts> <Catalyst id="1749" points="1987 1046" /> </Catalysts> <Properties> <displayName>SLC17A3-1 cotransports extracellular Na+ and Pi to cytosol</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="3759" reactomeId="936802" points="1554 401, 1554 395, 1554 394" position="1554 395" lineWidth="1.0"> <Inputs> <Input id="4825" points="1625 492" /> <Input id="77" points="1535 490" /> <Input id="78" points="1578 491" /> </Inputs> <Outputs> <Output id="79" points="1663 495" /> <Output id="4841" points="1551 359" /> <Output id="4838" points="1701 499" /> <Output id="81" points="1731 496" /> </Outputs> <Catalysts> <Catalyst id="3490" points="1482 394" /> </Catalysts> <Properties> <displayName>ATP7A transports cytosolic Cu1+ to extracellular region</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="3764" reactomeId="2730692" points="1529 966, 1490 965, 1461 966" position="1490 965" lineWidth="1.0"> <Inputs> <Input id="1347" points="1562 951" /> <Input id="1352" points="1602 1032" /> </Inputs> <Outputs> <Output id="42" points="1439 948" /> <Output id="1350" points="1414 1041" /> </Outputs> <Catalysts> <Catalyst id="1348" points="1490 996" /> </Catalysts> <Properties> <displayName>CLCN4/5/6 exchange Cl- for H+</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="3816" reactomeId="5252133" points="1513 863, 1514 862, 1582 888" position="1514 862" lineWidth="1.0" reactionType="Association"> <Inputs> <Input id="3817" points="1411 894" /> <Input id="3818" points="1467 888" /> </Inputs> <Outputs> <Output id="3819" /> </Outputs> <Properties> <displayName>ATP6AP1 binds V-ATPase</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="3929" reactomeId="9650165" points="2404 326, 2403 326, 2498 376" position="2403 326" lineWidth="1.0" reactionType="Association"> <Inputs> <Input id="3930" points="2398 378" /> <Input id="3940" points="2384 308" /> </Inputs> <Outputs> <Output id="2242" /> </Outputs> <Properties> <displayName>ASIC trimers bind H+</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="3954" reactomeId="9649963" points="2229 318, 2229 317, 2186 368" position="2229 317" lineWidth="1.0" reactionType="Association"> <Inputs> <Input id="3955" points="2229 285" /> <Input id="3956" points="2274 379" /> </Inputs> <Outputs> <Output id="3958" /> </Outputs> <Properties> <displayName>ASIC3 channel blockers bind ASIC3 trimer</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.EntitySetAndMemberLink id="3957" points="2326 393, 2352 393" position="2339 393" lineWidth="0.5" lineColor="0 0 0"> <Inputs> <Input id="3956" /> </Inputs> <Outputs> <Output id="3930" /> </Outputs> </org.gk.render.EntitySetAndMemberLink> <org.gk.render.RenderableReaction id="4105" reactomeId="9659568" points="2782 701, 3019 517, 3159 697" position="3019 517" lineWidth="1.0"> <Inputs> <Input id="2311" /> </Inputs> <Outputs> <Output id="2313" /> </Outputs> <Catalysts> <Catalyst id="4842" points="3025 488" /> </Catalysts> <Activators> <Activator id="2902" points="2981 836, 2833 774" /> <Activator id="2327" points="2876 552" /> </Activators> <Properties> <displayName>ANO1 transports cytosolic Cl- to extracellular region</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="4121" reactomeId="9659611" points="3015 394, 3015 394, 2960 391" position="3015 394" lineWidth="1.0" reactionType="Association"> <Inputs> <Input id="4106" points="3020 426" /> <Input id="4122" points="3033 352" /> </Inputs> <Outputs> <Output id="4123" /> </Outputs> <Properties> <displayName>ANO1 inhibitors bind ANO1</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="4184" reactomeId="9684068" points="511 298, 511 298, 480 365" position="511 298" lineWidth="1.0" reactionType="Association"> <Inputs> <Input id="4185" points="535 245" /> <Input id="112" points="549 363" /> </Inputs> <Outputs> <Output id="4186" /> </Outputs> <Properties> <displayName>ATP1A:ATP1B:FXYD binds cardiac glycosides</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="4213" reactomeId="9701055" points="2650 1693, 2585 1637, 2641 1548" position="2585 1637" lineWidth="1.0"> <Inputs> <Input id="4224" /> </Inputs> <Outputs> <Output id="4222" /> </Outputs> <Catalysts> <Catalyst id="4391" points="2529 1637" /> </Catalysts> <Activators> <Activator id="3634" points="2372 1508, 2585 1522" /> </Activators> <Properties> <displayName>TRPA1 tetramer transports Ca2+ from extracellular region to cytosol</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="4227" reactomeId="9701141" points="2679 1693, 2728 1636, 2661 1548" position="2728 1636" lineWidth="1.0"> <Inputs> <Input id="4224" /> </Inputs> <Outputs> <Output id="4222" /> </Outputs> <Catalysts> <Catalyst id="4453" points="2763 1636" /> </Catalysts> <Activators> <Activator id="3634" points="2372 1504, 2727 1504" /> </Activators> <Properties> <displayName>TRPV1 transports Ca2+ from extracellular region to cytosol</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="4287" reactomeId="9701064" points="2915 1702, 2914 1702, 2914 1658" position="2914 1702" lineWidth="1.0" reactionType="Association"> <Inputs> <Input id="4288" points="2966 1702" /> <Input id="4453" points="2810 1650" /> </Inputs> <Outputs> <Output id="4289" /> </Outputs> <Properties> <displayName>TRPV1 binds TRPV1 agonists</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="4510" reactomeId="9701147" points="3019 1542, 3019 1543, 3019 1494" position="3019 1543" lineWidth="1.0" reactionType="Association"> <Inputs> <Input id="4511" points="3078 1566" /> <Input id="4453" points="2817 1626" /> </Inputs> <Outputs> <Output id="4512" /> </Outputs> <Properties> <displayName>TRPV1 binds TRPV1 blockers</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="4558" reactomeId="9701211" points="2455 1699, 2455 1699, 2401 1659" position="2455 1699" lineWidth="1.0" reactionType="Association"> <Inputs> <Input id="4559" points="2455 1728" /> <Input id="4391" points="2481 1659" /> </Inputs> <Outputs> <Output id="4560" /> </Outputs> <Properties> <displayName>TRPA1 tetramer binds TRPA1 antagonists</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="4616" reactomeId="9727198" points="1197 462, 1142 462, 1081 462" position="1142 462" lineWidth="1.0"> <Inputs> <Input id="4617" points="1220 478" /> <Input id="4618" points="1221 456" /> <Input id="4626" points="1197 512" /> <Input id="4630" points="1197 363" /> </Inputs> <Outputs> <Output id="4619" points="1052 449" /> <Output id="4622" points="1081 368" /> <Output id="4624" points="1053 474" /> <Output id="4628" points="1081 547" /> </Outputs> <Catalysts> <Catalyst id="4620" points="1142 408" /> </Catalysts> <Properties> <displayName>ATP4A:ATP4B exchanges K+ for H+</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="4632" reactomeId="9727188" points="1183 304, 1183 304, 1278 372" position="1183 304" lineWidth="1.0" reactionType="Association"> <Inputs> <Input id="4620" points="1147 379" /> <Input id="4772" points="1183 268" /> </Inputs> <Outputs> <Output id="4634" /> </Outputs> <Properties> <displayName>ATP4A:ATP4B binds PPIs</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="4798" reactomeId="9774547" points="1483 1309, 1507 1309, 1550 1308" position="1507 1309" lineWidth="1.0"> <Inputs> <Input id="4799" points="1405 1228" /> <Input id="2043" points="1465 1325" /> </Inputs> <Outputs> <Output id="2046" points="1597 1210" /> <Output id="4800" points="1588 1339" /> </Outputs> <Catalysts> <Catalyst id="4795" points="1510 1254" /> </Catalysts> <Properties> <displayName>SLC9B2 exchanges Li+ for H+</displayName> </Properties> </org.gk.render.RenderableReaction> </Edges> <Pathways /> </Process> |
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No pathways have been reviewed or authored by Diagram of Ion channel transport (984845)
