Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Details on Person GOCAM MEN1 binds SMAD2/3:SMAD4 heterotrimer

Class:Id	Reaction:9846557
_displayName	GOCAM MEN1 binds SMAD2/3:SMAD4 heterotrimer
_timestamp	2023-10-11 22:24:55
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9846550] D'Eustachio, Peter, 2023-10-11
input	[DefinedSet:173511] p-2S-SMAD2,3:SMAD4 [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:2186626] MEN1 [nucleoplasm] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:2186644] Inactivation of menin, a Smad3-interacting protein, blocks transforming growth factor type beta signaling [LiteratureReference:2186647] Impaired Transforming Growth Factor-? (TGF-?) Transcriptional Activity and Cell Proliferation Control of a Menin In-frame Deletion Mutant Associated with Multiple Endocrine Neoplasia Type 1 (MEN1) [LiteratureReference:2186646] Menin is required for bone morphogenetic protein 2- and transforming growth factor beta-regulated osteoblastic differentiation through interaction with Smads and Runx2
name	GOCAM MEN1 binds SMAD2/3:SMAD4 heterotrimer
negativePrecedingEvent	[NegativePrecedingEvent:9754435] Futile Cycle: Ubiquitination of SKI/SKIL by RNF111/SMURF2
output	[Complex:2186642] p-2S-SMAD2,3:SMAD4:MEN1 [nucleoplasm] [Homo sapiens]
precedingEvent	[BlackBoxEvent:9846551] GOCAM The SMAD2/3:SMAD4 complex transfers to the nucleus [Homo sapiens] [Reaction:9846552] GOCAM Phosphorylated SMAD2 and SMAD3 form a complex with SMAD4 [Homo sapiens]
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9846567] R-HSA-9846557.1
summation	[Summation:2186724] MEN1 (menin), a transcription factor tumor suppressor mutate...
(hasEvent)	[Pathway:9846544] GOCAM SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription [Homo sapiens]
[Change default viewing format]

No pathways have been reviewed or authored by GOCAM MEN1 binds SMAD2/3:SMAD4 heterotrimer (9846557)