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Details on Person GOCAM FURIN gene transcription is stimulated by SMAD2/SMAD3:SMAD4

Class:IdBlackBoxEvent:9846549
_displayNameGOCAM FURIN gene transcription is stimulated by SMAD2/SMAD3:SMAD4
_timestamp2023-10-11 22:24:55
compartment[Compartment:7660] nucleoplasm
created[InstanceEdit:9846550] D'Eustachio, Peter, 2023-10-11
input[EntityWithAccessionedSequence:8981023] FURIN gene [nucleoplasm] [Homo sapiens]
isChimericFALSE
literatureReference[LiteratureReference:9737470] Involvement of Smads in TGFbeta1-induced furin (fur) transcription
[LiteratureReference:9737466] TGF-β1 Increases GDNF Production by Upregulating the Expression of GDNF and Furin in Human Granulosa-Lutein Cells
nameGOCAM FURIN gene transcription is stimulated by SMAD2/SMAD3:SMAD4
negativePrecedingEvent[NegativePrecedingEvent:9754424] Futile Cycle: Ubiquitination of SKI/SKIL by RNF111/SMURF2
output[EntityWithAccessionedSequence:157049] FURIN [Golgi membrane] [Homo sapiens]
precedingEvent
regulatedBy[PositiveGeneExpressionRegulation:9733201] Positive gene expression regulation by 'p-2S-SMAD2,3:SMAD4 [nucleoplasm]'
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9846586] R-HSA-9846549.1
summation[Summation:9737405] TGFB1 increases the expression of furin in rat synoviocytes ...
(hasEvent)[Pathway:9846544] GOCAM SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription [Homo sapiens]
(precedingEvent)[BlackBoxEvent:9846560] GOCAM FURIN translocates to the plasma membrane [Homo sapiens]
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No pathways have been reviewed or authored by GOCAM FURIN gene transcription is stimulated by SMAD2/SMAD3:SMAD4 (9846549)
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