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Details on Person GOCAM p-2S-SMAD2,3:SMAD4 binds JUNB gene promoter

Class:IdReaction:9846547
_displayNameGOCAM p-2S-SMAD2,3:SMAD4 binds JUNB gene promoter
_timestamp2023-10-11 22:24:55
compartment[Compartment:7660] nucleoplasm
created[InstanceEdit:9846550] D'Eustachio, Peter, 2023-10-11
input[DefinedSet:173511] p-2S-SMAD2,3:SMAD4 [nucleoplasm] [Homo sapiens]
[EntityWithAccessionedSequence:2187294] JUNB gene [nucleoplasm] [Homo sapiens]
isChimericFALSE
literatureReference[LiteratureReference:2187286] Smad3-Smad4 and AP-1 complexes synergize in transcriptional activation of the c-Jun promoter by transforming growth factor beta
nameGOCAM p-2S-SMAD2,3:SMAD4 binds JUNB gene promoter
negativePrecedingEvent[NegativePrecedingEvent:9754432] Futile Cycle: Ubiquitination of SKI/SKIL by RNF111/SMURF2
output[Complex:9736993] p-2S-SMAD2,3:SMAD4:JUNB gene [nucleoplasm] [Homo sapiens]
precedingEvent
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9846583] R-HSA-9846547.1
summation[Summation:9736991] SMAD2/3:SMAD4 heterotrimer binds SMAD binding site in the pr...
(hasEvent)[Pathway:9846544] GOCAM SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription [Homo sapiens]
(precedingEvent)[BlackBoxEvent:9846546] GOCAM SMAD2/3:SMAD4 complex positively regulates JUNB transcription [Homo sapiens]
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No pathways have been reviewed or authored by GOCAM p-2S-SMAD2,3:SMAD4 binds JUNB gene promoter (9846547)