Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Details on Person GOCAM Phosphorylation of EGFR by SRC kinase

Class:Id	Reaction:9846388
_displayName	GOCAM Phosphorylation of EGFR by SRC kinase
_timestamp	2023-10-20 21:33:43
catalystActivity	[CatalystActivity:179862] protein tyrosine kinase activity of SRC-1 [plasma membrane]
compartment	[Compartment:70101] cytosol [Compartment:876] plasma membrane [Compartment:984] extracellular region
created	[InstanceEdit:9846405] D'Eustachio, Peter, 2023-10-10
figure	[Figure:189925] /figures/egfr_P_by_src.jpg
input	[SimpleEntity:113592] ATP [cytosol] [SimpleEntity:113592] ATP [cytosol] [SimpleEntity:113592] ATP [cytosol] [SimpleEntity:113592] ATP [cytosol] [SimpleEntity:113592] ATP [cytosol] [SimpleEntity:113592] ATP [cytosol] [SimpleEntity:113592] ATP [cytosol] [SimpleEntity:113592] ATP [cytosol] [SimpleEntity:113592] ATP [cytosol] [SimpleEntity:113592] ATP [cytosol] [SimpleEntity:113592] ATP [cytosol] [SimpleEntity:113592] ATP [cytosol] [Complex:9624420] EGF-like ligands:EGFR dimer [plasma membrane] [Homo sapiens]
literatureReference	[LiteratureReference:179802] In vitro phosphorylation of the epidermal growth factor receptor autophosphorylation domain by c-src: identification of phosphorylation sites and c-src SH2 domain binding sites
modified	[InstanceEdit:9846469] D'Eustachio, Peter, 2023-10-10 [InstanceEdit:9851295] D'Eustachio, Peter, 2023-10-20
name	GOCAM Phosphorylation of EGFR by SRC kinase ATP + L-tyrosyl-(protein) => ADP + H(+) + O-phospho-L-tyrosyl-(protein)
output	[SimpleEntity:29370] ADP [cytosol] [SimpleEntity:29370] ADP [cytosol] [SimpleEntity:29370] ADP [cytosol] [SimpleEntity:29370] ADP [cytosol] [SimpleEntity:29370] ADP [cytosol] [SimpleEntity:29370] ADP [cytosol] [SimpleEntity:29370] ADP [cytosol] [SimpleEntity:29370] ADP [cytosol] [SimpleEntity:29370] ADP [cytosol] [SimpleEntity:29370] ADP [cytosol] [SimpleEntity:29370] ADP [cytosol] [SimpleEntity:29370] ADP [cytosol] [Complex:9624425] EGF-like ligands:p-6Y EGFR dimer [plasma membrane] [Homo sapiens] [SimpleEntity:70106] H+ [cytosol] [SimpleEntity:70106] H+ [cytosol] [SimpleEntity:70106] H+ [cytosol] [SimpleEntity:70106] H+ [cytosol] [SimpleEntity:70106] H+ [cytosol] [SimpleEntity:70106] H+ [cytosol] [SimpleEntity:70106] H+ [cytosol] [SimpleEntity:70106] H+ [cytosol] [SimpleEntity:70106] H+ [cytosol] [SimpleEntity:70106] H+ [cytosol] [SimpleEntity:70106] H+ [cytosol] [SimpleEntity:70106] H+ [cytosol]
precedingEvent	[Reaction:9846387] GOCAM EGFR dimerization [Homo sapiens] [Reaction:9846408] GOCAM EGFR binds EGF ligand [Homo sapiens]
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9846436] R-HSA-9846388.1
structureModified	[InstanceEdit:9851295] D'Eustachio, Peter, 2023-10-20
summation	[Summation:188445] Besides autophosphorylation, EGFR can become tyrosine-phosph...
(hasEvent)	[Pathway:9846354] GOCAM Signaling by EGFR [Homo sapiens]
(precedingEvent)	[Reaction:9846371] GOCAM PTPRK dephosphorylates p-6Y-EGFR [Homo sapiens] [Reaction:9846377] GOCAM GRB2:SOS1 complex binds to EGF:EGFR complex [Homo sapiens] [Reaction:9846379] GOCAM Phospholipase C-gamma1 binds to the activated EGF receptor [Homo sapiens]
[Change default viewing format]

No pathways have been reviewed or authored by GOCAM Phosphorylation of EGFR by SRC kinase (9846388)