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Query author contributions in Reactome

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Details on Person GOCAM Binding of CBL to EGFR

Class:IdReaction:9846375
_displayNameGOCAM Binding of CBL to EGFR
_timestamp2023-10-10 21:23:32
compartment[Compartment:876] plasma membrane
[Compartment:984] extracellular region
created[InstanceEdit:9846405] D'Eustachio, Peter, 2023-10-10
input[EntityWithAccessionedSequence:112199] CBL [cytosol] [Homo sapiens]
[EntityWithAccessionedSequence:112199] CBL [cytosol] [Homo sapiens]
[Complex:9624425] EGF-like ligands:p-6Y EGFR dimer [plasma membrane] [Homo sapiens]
literatureReference[LiteratureReference:183045] Direct interaction of Cbl with pTyr 1045 of the EGF receptor (EGFR) is required to sort the EGFR to lysosomes for degradation
modified[InstanceEdit:9846469] D'Eustachio, Peter, 2023-10-10
nameGOCAM Binding of CBL to EGFR
output[Complex:182960] EGF-like ligands:p-6Y-EGFR:CBL [plasma membrane] [Homo sapiens]
precedingEvent
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9846467] R-HSA-9846375.1
summation[Summation:183088] Phosphorylation at tyrosine Y1069 (i.e. Y1045 in the mature ...
(hasEvent)[Pathway:9846353] GOCAM EGFR downregulation [Homo sapiens]
(precedingEvent)[Reaction:9846381] GOCAM Phosphorylation of CBL (EGFR:CBL) [Homo sapiens]
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No pathways have been reviewed or authored by GOCAM Binding of CBL to EGFR (9846375)