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Details on Person GOCAM Pro-EGF is cleaved to form mature EGF

Class:IdReaction:9846368
_displayNameGOCAM Pro-EGF is cleaved to form mature EGF
_timestamp2023-10-13 16:54:10
catalystActivity[CatalystActivity:179871] metalloendopeptidase activity of ADAM:Zn2+ [plasma membrane]
compartment[Compartment:984] extracellular region
[Compartment:876] plasma membrane
created[InstanceEdit:9846405] D'Eustachio, Peter, 2023-10-10
goBiologicalProcess[GO_BiologicalProcess:2132710] epidermal growth factor receptor ligand maturation
inferredFrom
input[EntityWithAccessionedSequence:179888] Pro-EGF [plasma membrane] [Homo sapiens]
modified[InstanceEdit:9846469] D'Eustachio, Peter, 2023-10-10
[InstanceEdit:9851197] D'Eustachio, Peter, 2023-10-13
nameGOCAM Pro-EGF is cleaved to form mature EGF
output[EntityWithAccessionedSequence:179863] EGF [extracellular region] [Homo sapiens]
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9846445] R-HSA-9846368.1
summation[Summation:179818] Ligands of the epidermal growth factor receptor (EGFR) are ...
(hasEvent)[Pathway:9846354] GOCAM Signaling by EGFR [Homo sapiens]
(precedingEvent)[Reaction:9846408] GOCAM EGFR binds EGF ligand [Homo sapiens]
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No pathways have been reviewed or authored by GOCAM Pro-EGF is cleaved to form mature EGF (9846368)
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