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Details on Person GOCAM STRAP binds phosphorylated TGF-beta receptor complex

Class:Id	Reaction:9846240
_displayName	GOCAM STRAP binds phosphorylated TGF-beta receptor complex
_doRelease	FALSE
_timestamp	2023-10-09 23:12:56
compartment	[Compartment:876] plasma membrane [Compartment:70101] cytosol [Compartment:984] extracellular region
created	[InstanceEdit:9846244] D'Eustachio, Peter, 2023-10-09
inferredFrom	[Reaction:2128982] Strap binds phosphorylated TGF-beta receptor complex [Homo sapiens]
input	[EntityWithAccessionedSequence:2127556] STRAP [cytosol] [Homo sapiens] [Complex:170841] TGFB1:TGFBR2:p-TGFBR1 [plasma membrane] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:2127560] Identification of STRAP, a novel WD domain protein in transforming growth factor-beta signaling
modified	[InstanceEdit:9846290] D'Eustachio, Peter, 2023-10-09
name	GOCAM STRAP binds phosphorylated TGF-beta receptor complex
output	[Complex:2127564] TGFB1:p-TGFBR:STRAP [plasma membrane] [Homo sapiens]
precedingEvent	[Reaction:9846197] GOCAM TGFBR2 phosphorylates TGFBR1 [Homo sapiens] [Reaction:9846186] GOCAM TGFBR2 recruits TGFBR1 [Homo sapiens]
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9846272] R-HSA-9846240.1
summation	[Summation:2127610] STRAP (serine-threonine kinase receptor-associated protein) ...
(hasEvent)	[Pathway:9846195] GOCAM Downregulation of TGF-beta receptor signaling [Homo sapiens]
(precedingEvent)	[Reaction:9846258] GOCAM STRAP stabilizes interaction of activated TGF-beta receptor complex with SMAD7 [Homo sapiens]
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No pathways have been reviewed or authored by GOCAM STRAP binds phosphorylated TGF-beta receptor complex (9846240)