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Details on Person GOCAM BAMBI interferes with the interaction of type I receptor with type II receptor

Class:IdReaction:9846233
_displayNameGOCAM BAMBI interferes with the interaction of type I receptor with type II receptor
_doReleaseFALSE
_timestamp2023-10-09 23:12:25
compartment[Compartment:876] plasma membrane
created[InstanceEdit:9846244] D'Eustachio, Peter, 2023-10-09
goBiologicalProcess[GO_BiologicalProcess:23765] negative regulation of transforming growth factor beta receptor signaling pathway
input[EntityWithAccessionedSequence:173484] BAMBI [plasma membrane] [Homo sapiens]
[Complex:170841] TGFB1:TGFBR2:p-TGFBR1 [plasma membrane] [Homo sapiens]
[EntityWithAccessionedSequence:173478] SMAD7 [cytosol] [Homo sapiens]
literatureReference[LiteratureReference:3009244] Silencing of TGF-beta signalling by the pseudoreceptor BAMBI
[LiteratureReference:480561] Human BAMBI cooperates with Smad7 to inhibit transforming growth factor-beta signaling
modified[InstanceEdit:9846290] D'Eustachio, Peter, 2023-10-09
nameGOCAM BAMBI interferes with the interaction of type I receptor with type II receptor
output[Complex:173509] TGFB1: TGFBR2: p-TGFBR1: BAMBI: SMAD7 [plasma membrane] [Homo sapiens]
precedingEvent
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9846275] R-HSA-9846233.1
summation[Summation:3027879] BAMBI (BMP and activin membrane-bound inhibitor) is a transm...
(hasEvent)[Pathway:9846195] GOCAM Downregulation of TGF-beta receptor signaling [Homo sapiens]
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