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Details on Person GOCAM Secretion and activation of the latent large complex of TGF-beta-2

Class:IdBlackBoxEvent:9846206
_displayNameGOCAM Secretion and activation of the latent large complex of TGF-beta-2
_doReleaseFALSE
_timestamp2023-10-09 23:12:04
compartment[Compartment:17963] Golgi lumen
[Compartment:984] extracellular region
created[InstanceEdit:9846202] D'Eustachio, Peter, 2023-10-09
input[Complex:9729953] TGF-beta-2:LAP2 [Golgi lumen] [Homo sapiens]
literatureReference[LiteratureReference:9737414] Physicochemical activation of recombinant latent transforming growth factor-beta's 1, 2, and 3
[LiteratureReference:9737438] Recombinant production, purification, crystallization, and structure analysis of human transforming growth factor β2 in a new conformation
modified[InstanceEdit:9846244] D'Eustachio, Peter, 2023-10-09
nameGOCAM Secretion and activation of the latent large complex of TGF-beta-2
output[Complex:2395253] TGFB2:LAP2 [extracellular region] [Homo sapiens]
precedingEvent
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9846222] R-HSA-9846206.1
summation[Summation:9737415] Similar to TGFB1, TGFB2 is also secreted as a latent large c...
(hasEvent)[Pathway:9846196] GOCAM TGF-beta receptor signaling activates SMADs [Homo sapiens]
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