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Query author contributions in Reactome

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Details on Person GOCAM Cholesterol-dependent TGFB signaling activation

Class:IdReaction:9846203
_displayNameGOCAM Cholesterol-dependent TGFB signaling activation
_doReleaseFALSE
_timestamp2023-10-09 23:11:43
compartment[Compartment:70101] cytosol
[Compartment:876] plasma membrane
created[InstanceEdit:9846202] D'Eustachio, Peter, 2023-10-09
input[EntityWithAccessionedSequence:170839] TGFBR1 [plasma membrane] [Homo sapiens]
isChimericFALSE
literatureReference[LiteratureReference:9736771] Sterol Regulatory Element Binding Protein (SREBP)-1 is a novel regulator of the Transforming Growth Factor (TGF)-β receptor I (TβRI) through exosomal secretion
[LiteratureReference:9736793] Cholesterol Pathway Inhibition Induces TGF-β Signaling to Promote Basal Differentiation in Pancreatic Cancer
modified[InstanceEdit:9846244] D'Eustachio, Peter, 2023-10-09
nameGOCAM Cholesterol-dependent TGFB signaling activation
output[Complex:170863] p-TGFBR1 [plasma membrane] [Homo sapiens]
regulatedBy[PositiveRegulation:9736746] Positive regulation by 'SREBF1-1(1-490) [cytosol]'
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9846219] R-HSA-9846203.1
summation[Summation:9736777] Cholesterol is an important structural component of lipid ra...
(hasEvent)[Pathway:9846196] GOCAM TGF-beta receptor signaling activates SMADs [Homo sapiens]
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No pathways have been reviewed or authored by GOCAM Cholesterol-dependent TGFB signaling activation (9846203)
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