Reactome: A Curated Pathway Database
THIS SITE IS USED FOR CURATION AND TESTING
IT IS NOT STABLE, IS LINKED TO AN INCOMPLETE DATA SET, AND IS NOT MONITORED FOR PERFORMANCE. WE STRONGLY RECOMMEND THE USE OF OUR PUBLIC SITE

Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Name Email address

Details on Person GOCAM Endofin facilitates the binding of SMAD2 with SMAD4

Class:IdReaction:9846199
_displayNameGOCAM Endofin facilitates the binding of SMAD2 with SMAD4
_doReleaseFALSE
_timestamp2023-10-09 23:11:48
created[InstanceEdit:9846202] D'Eustachio, Peter, 2023-10-09
input[EntityWithAccessionedSequence:3006353] SMAD2 [cytosol] [Homo sapiens]
[EntityWithAccessionedSequence:170862] SMAD4 [cytosol] [Homo sapiens]
isChimericFALSE
literatureReference[LiteratureReference:3009206] Endofin, a FYVE domain protein, interacts with Smad4 and facilitates transforming growth factor-beta signaling
modified[InstanceEdit:9846244] D'Eustachio, Peter, 2023-10-09
nameGOCAM Endofin facilitates the binding of SMAD2 with SMAD4
output[Complex:9736753] SMAD2:SMAD4 [cytosol] [Homo sapiens]
regulatedBy[PositiveRegulation:9736747] Positive regulation by 'ZFYVE16 [early endosome membrane]'
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9846213] R-HSA-9846199.1
summation[Summation:9736781] Endofin, a member of the FYVE domain protein endofin, facili...
(hasEvent)[Pathway:9846196] GOCAM TGF-beta receptor signaling activates SMADs [Homo sapiens]
[Change default viewing format]
No pathways have been reviewed or authored by GOCAM Endofin facilitates the binding of SMAD2 with SMAD4 (9846199)