Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Details on Person GOCAM TGFBR2 phosphorylates TGFBR1

Class:Id	Reaction:9846197
_displayName	GOCAM TGFBR2 phosphorylates TGFBR1
_doRelease	FALSE
_timestamp	2023-10-09 23:12:09
catalystActivity	[CatalystActivity:170856] transforming growth factor beta receptor activity, type II of TGFB1:TGFBR2:TGFBR1 [plasma membrane]
compartment	[Compartment:70101] cytosol [Compartment:876] plasma membrane
created	[InstanceEdit:9846202] D'Eustachio, Peter, 2023-10-09
input	[Complex:170840] TGFB1:TGFBR2:TGFBR1 [plasma membrane] [Homo sapiens] [SimpleEntity:113592] ATP [cytosol] [SimpleEntity:113592] ATP [cytosol] [SimpleEntity:113592] ATP [cytosol] [SimpleEntity:113592] ATP [cytosol] [SimpleEntity:113592] ATP [cytosol] [SimpleEntity:113592] ATP [cytosol] [SimpleEntity:113592] ATP [cytosol] [SimpleEntity:113592] ATP [cytosol] [SimpleEntity:113592] ATP [cytosol] [SimpleEntity:113592] ATP [cytosol] [SimpleEntity:113592] ATP [cytosol] [SimpleEntity:113592] ATP [cytosol]
literatureReference	[LiteratureReference:175963] Mechanism of activation of the TGF-beta receptor [LiteratureReference:175965] Phosphorylation of Ser165 in TGF-beta type I receptor modulates TGF-beta1-induced cellular responses [LiteratureReference:4127454] The type I TGF-beta receptor is covalently modified and regulated by sumoylation
modified	[InstanceEdit:9846244] D'Eustachio, Peter, 2023-10-09
name	GOCAM TGFBR2 phosphorylates TGFBR1 Type II receptor phosphorylates type I receptor
output	[Complex:170841] TGFB1:TGFBR2:p-TGFBR1 [plasma membrane] [Homo sapiens] [SimpleEntity:29370] ADP [cytosol] [SimpleEntity:29370] ADP [cytosol] [SimpleEntity:29370] ADP [cytosol] [SimpleEntity:29370] ADP [cytosol] [SimpleEntity:29370] ADP [cytosol] [SimpleEntity:29370] ADP [cytosol] [SimpleEntity:29370] ADP [cytosol] [SimpleEntity:29370] ADP [cytosol] [SimpleEntity:29370] ADP [cytosol] [SimpleEntity:29370] ADP [cytosol] [SimpleEntity:29370] ADP [cytosol] [SimpleEntity:29370] ADP [cytosol]
precedingEvent	[Reaction:9846186] GOCAM TGFBR2 recruits TGFBR1 [Homo sapiens] [Reaction:9846185] GOCAM Dimeric TGF-beta-1 binds to the receptor [Homo sapiens]
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9846228] R-HSA-9846197.1
summation	[Summation:176016] Formation of the hetero-tetrameric TGF-beta-1 receptor compl...
(hasEvent)	[Pathway:9846196] GOCAM TGF-beta receptor signaling activates SMADs [Homo sapiens]
(precedingEvent)	[Reaction:9846201] GOCAM An anchoring protein, ZFYVE9 (SARA), recruits SMAD2/3 [Homo sapiens] [Reaction:9846240] GOCAM STRAP binds phosphorylated TGF-beta receptor complex [Homo sapiens]
[Change default viewing format]

No pathways have been reviewed or authored by GOCAM TGFBR2 phosphorylates TGFBR1 (9846197)