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Details on Person GOCAM Latent TGF-beta-3 is cleaved by FURIN

Class:Id	Reaction:9846194
_displayName	GOCAM Latent TGF-beta-3 is cleaved by FURIN
_doRelease	FALSE
_timestamp	2023-10-09 23:11:58
catalystActivity	[CatalystActivity:156993] serine-type endopeptidase activity of FURIN [Golgi membrane]
compartment	[Compartment:17963] Golgi lumen
created	[InstanceEdit:9846202] D'Eustachio, Peter, 2023-10-09
inferredFrom	[Reaction:170844] Latent TGF-beta-1 is cleaved by FURIN [Homo sapiens] [Reaction:9729936] Latent TGF-beta-2 is cleaved by FURIN [Homo sapiens]
input	[Complex:9729942] Pre-TGFB3 complex [Golgi lumen] [Homo sapiens]
isChimeric	FALSE
modified	[InstanceEdit:9846244] D'Eustachio, Peter, 2023-10-09
name	GOCAM Latent TGF-beta-3 is cleaved by FURIN
output	[Complex:9729952] TGF-beta-3:LAP3 [Golgi lumen] [Homo sapiens]
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9846232] R-HSA-9846194.1
summation	[Summation:9737410] Cleavage of TGFB3 precursor by FURIN protease has not been e...
(hasEvent)	[Pathway:9846196] GOCAM TGF-beta receptor signaling activates SMADs [Homo sapiens]
(precedingEvent)	[BlackBoxEvent:9846204] GOCAM Secretion and activation of the latent large complex of TGF-beta-3 [Homo sapiens]
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No pathways have been reviewed or authored by GOCAM Latent TGF-beta-3 is cleaved by FURIN (9846194)