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Details on Person Whole Exome Sequencing reveals NOTCH1 mutations in anaplastic large cell lymphoma and points to Notch both as a key pathway and a potential therapeutic target

Class:IdLiteratureReference:9846160
_displayNameWhole Exome Sequencing reveals NOTCH1 mutations in anaplastic large cell lymphoma and points to Notch both as a key pathway and a potential therapeutic target
_timestamp2023-10-08 12:55:19
author[Person:9843026] Larose, Hugo
[Person:9843044] Prokoph, Nina
[Person:9843039] Matthews, Jamie D
[Person:9845994] Schlederer, Michaela
[Person:9843060] Högler, Sandra
[Person:9846162] Alsulami, Ali F
[Person:9724955] Ducray, Stephen P
[Person:9846158] Nuglozeh, Edem
[Person:9846163] Fazaludeen, Feroze M S
[Person:9846155] Elmouna, Ahmed
[Person:9700313] Ceccon, Monica
[Person:9699790] Mologni, Luca
[Person:9647075] Gambacorti-Passerini, Carlo
[Person:5621745] Hoefler, Gerald
[Person:9843040] Lobello, Cosimo
[Person:5251078] Pospisilova, Sarka
[Person:9843028] Janíková, Andrea
[Person:9725261] Woessmann, Wilhelm
[Person:9710765] Damm-Welk, Christine
[Person:9846165] Zimmermann, Martin
[Person:9846153] Federova, Alina
[Person:9846157] Malone, Andrea
[Person:9846159] Smith, Owen
[Person:9701291] Wasik, Mariusz
[Person:9648424] Inghirami, Giorgio
[Person:8849781] Lamant, Laurence
[Person:2044975] Blundell, TL
[Person:9710770] Klapper, Wolfram
[Person:9725266] Merkel, Olaf
[Person:9846156] Burke, Amos G A
[Person:9846164] Mian, Shahid
[Person:9846161] Ashankyty, Ibraheem
[Person:9725276] Kenner, Lukas
[Person:9724959] Turner, Suzanne D
created[InstanceEdit:9846154] Rothfels, Karen, 2023-10-08
journalHaematologica
pages1693-1704
pubMedIdentifier32327503
titleWhole Exome Sequencing reveals NOTCH1 mutations in anaplastic large cell lymphoma and points to Notch both as a key pathway and a potential therapeutic target
volume106
year2021
(literatureReference)[RegulationReference:9851039] Positive gene expression regulation by 'p-Y705,S727 -STAT3 dimer: NOTCH gene [nucleoplasm]' Whole Exome Sequencing reveals NOTCH1 mutations in anaplastic large cell lymphoma and points to Notch both as a key pathway and a potential therapeutic target
[Reaction:9851122] p-Y705,S727 STAT3 dimer binds NOTCH gene [Homo sapiens]
[BlackBoxEvent:9851123] NPM1-ALK- and p-STAT3-dependent NOTCH gene expression [Homo sapiens]
[Complex:9850937] p-Y705,S727 -STAT3 dimer: NOTCH gene [nucleoplasm] [Homo sapiens]
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