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Details on Person Kinesin-8 is a plus-end-directed dimeric kinesin with an int...

Class:Id	Summation:984592
_displayName	Kinesin-8 is a plus-end-directed dimeric kinesin with an int...
_timestamp	2010-11-08 17:42:12
created	[InstanceEdit:984623] Jupe, S, 2010-11-02
literatureReference	[LiteratureReference:984690] Yeast kinesin-8 depolymerizes microtubules in a length-dependent manner [LiteratureReference:984757] Mitochondrial association of a plus end-directed microtubule motor expressed during mitosis in Drosophila [LiteratureReference:984735] The kinesin-8 motor Kif18A suppresses kinetochore movements to control mitotic chromosome alignment [LiteratureReference:984778] SnapShot: motor proteins in spindle assembly
modified	[InstanceEdit:997250] Jupe, S, 2010-11-08
text	Kinesin-8 is a plus-end-directed dimeric kinesin with an internal motor domain (Loughlin et al. 2008) that can depolymerize stable microtubuless specifically at their plus-ends (Pereira et al. 1997) in a length-dependent manner (Varga et al. 2006). Human kinesin-8 KIF18A is believed to promote chromosome congression by attenuating chromosome oscillation magnitudes (Stumpff et al. 2008).
(summation)	[Reaction:984609] Kinesin-8 is a dimer [Homo sapiens]
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