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Details on Person B4GALT5/6 transfer Gal to GlcCer

Class:IdReaction:9845285
_displayNameB4GALT5/6 transfer Gal to GlcCer
_doReleaseFALSE
_timestamp2023-11-09 10:23:12
authored[InstanceEdit:9845269] Stephan, Ralf, 2023-10-01
catalystActivity[CatalystActivity:9845277] UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity of B4GALT5/6 [Golgi membrane]
compartment[Compartment:20699] Golgi membrane
[Compartment:17963] Golgi lumen
created[InstanceEdit:9845283] Stephan, Ralf, 2023-10-01
input[SimpleEntity:735682] UDP-Gal [Golgi lumen]
[SimpleEntity:1660674] GlcCer [Golgi membrane]
isChimericFALSE
literatureReference[LiteratureReference:9845271] Establishment of HeLa cell mutants deficient in sphingolipid-related genes using TALENs
[LiteratureReference:9845284] Convergence: Lactosylceramide-Centric Signaling Pathways Induce Inflammation, Oxidative Stress, and Other Phenotypic Outcomes
[LiteratureReference:9845287] β4GalT6 is involved in the synthesis of lactosylceramide with less intensity than β4GalT5
modified[InstanceEdit:9851294] Stephan, Ralf, 2023-10-20
[InstanceEdit:9852990] Stephan, Ralf, 2023-11-09
nameB4GALT5/6 transfer Gal to GlcCer
output[SimpleEntity:205687] UDP [Golgi lumen]
[SimpleEntity:425969] H+ [Golgi lumen]
[SimpleEntity:9844874] LacCer-d18 [Golgi membrane]
precedingEvent
stableIdentifier[StableIdentifier:9845289] R-NUL-9845285.1
summation[Summation:9845275] Beta-1,4-galactosyltransferases 5 and 6 (B4GALT5/6) catalyze...
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