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Details on Person Asvasiran binds N mRNA

Class:IdReaction:9845192
_displayNameAsvasiran binds N mRNA
_doReleaseTRUE
_timestamp2023-11-13 21:26:55
authored[InstanceEdit:9845157] Stephan, Ralf, 2023-09-27
compartment[Compartment:70101] cytosol
created[InstanceEdit:9845183] Stephan, Ralf, 2023-09-28
disease[Disease:9833927] respiratory syncytial virus infectious disease
edited[InstanceEdit:9845183] Stephan, Ralf, 2023-09-28
input[RNADrug:9845174] asvasiran [cytosol]
[EntityWithAccessionedSequence:9828647] m7G(5')pppAm-capped,polyadenylated N mRNA [cytosol] [Human respiratory syncytial virus A]
isChimericFALSE
literatureReference[LiteratureReference:9845264] Recent Advances in Inhaled Nanoformulations of Vaccines and Therapeutics Targeting Respiratory Viral Infections
[LiteratureReference:9845189] ALN-RSV01 for prevention of bronchiolitis obliterans syndrome after respiratory syncytial virus infection in lung transplant recipients
[LiteratureReference:9845250] A randomized, double-blind, placebo-controlled study of an RNAi-based therapy directed against respiratory syncytial virus
[LiteratureReference:9845263] RNA interference therapy in lung transplant patients infected with respiratory syncytial virus
modified[InstanceEdit:9845240] Stephan, Ralf, 2023-09-29
[InstanceEdit:9845256] Stephan, Ralf, 2023-09-30
[InstanceEdit:9850763] Orlic-Milacic, Marija, 2023-10-12
[InstanceEdit:9851889] Orlic-Milacic, Marija, 2023-11-01
[InstanceEdit:9852855] Orlic-Milacic, Marija, 2023-11-07
[InstanceEdit:9853081] Matthews, Lisa, 2023-11-13
nameAsvasiran binds N mRNA
output[Complex:9845187] asvasiran:N mRNA [cytosol] [Human respiratory syncytial virus A]
precedingEvent
relatedSpecies[Species:9717528] Human respiratory syncytial virus A
releaseDate2023-12-06
reviewed[InstanceEdit:9852848] Bergeron, Harrison Christopher, 2023-11-03
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9845193] R-HSA-9845192.1
summation[Summation:9845252] Asvasiran (ALN-RSV01) is a naked siRNA targeting the RSV nuc...
(hasEvent)[Pathway:9828642] Respiratory syncytial virus genome transcription [Homo sapiens]
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No pathways have been reviewed or authored by Asvasiran binds N mRNA (9845192)