Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Details on Person ST3GAL5 transfers NeuNAc to ceramides

Class:Id	Reaction:9844860
_displayName	ST3GAL5 transfers NeuNAc to ceramides
_doRelease	TRUE
_timestamp	2025-01-29 08:54:12
authored	[InstanceEdit:9844761] Stephan, Ralf, 2023-09-22
catalystActivity	[CatalystActivity:9844856] beta-galactoside (CMP) alpha-2,3-sialyltransferase activity of ST3GAL5 [Golgi membrane]
compartment	[Compartment:20699] Golgi membrane [Compartment:17963] Golgi lumen
created	[InstanceEdit:9844880] Stephan, Ralf, 2023-09-23
edited	[InstanceEdit:9851336] Stephan, Ralf, 2023-10-23
input	[DefinedSet:9844855] LacCer/GalCer/GA1/GA2 [Golgi membrane] [SimpleEntity:727815] CMP-Neu5Ac [Golgi lumen]
isChimeric	FALSE
literatureReference	[LiteratureReference:4086330] Expression cloning and functional characterization of human cDNA for ganglioside GM3 synthase [LiteratureReference:6785916] Ceramide glycosylation catalyzed by glucosylceramide synthase and cancer drug resistance [LiteratureReference:9844869] Human GM3 synthase: a new mRNA variant encodes an NH2-terminal extended form of the protein [LiteratureReference:9844872] Evidence supporting a late Golgi location for lactosylceramide to ganglioside GM3 conversion [LiteratureReference:9844854] Molecular identification, tissue distribution and subcellular localization of mST3GalV/GM3 synthase [LiteratureReference:9844875] Ganglioside GM3 Synthase Deficiency in Mouse Models and Human Patients [LiteratureReference:9844866] Mass spectrometric quantification of plasma glycosphingolipids in human GM3 ganglioside deficiency
modified	[InstanceEdit:9844958] Stephan, Ralf, 2023-09-25 [InstanceEdit:9844976] Stephan, Ralf, 2023-09-25 [InstanceEdit:9851294] Stephan, Ralf, 2023-10-20 [InstanceEdit:9851346] Stephan, Ralf, 2023-10-24 [InstanceEdit:9851350] Stephan, Ralf, 2023-10-24 [InstanceEdit:9851351] Stephan, Ralf, 2023-10-24 [InstanceEdit:9937068] Stephan, Ralf, 2025-01-29
name	ST3GAL5 transfers NeuNAc to ceramides
output	[DefinedSet:9844871] GM1/2/3/4 [Golgi membrane] [SimpleEntity:727810] CMP [Golgi lumen] [SimpleEntity:425969] H+ [Golgi lumen]
precedingEvent	[Reaction:6785933] UGT8 transfers Gal from UDP-Gal to CERA [Homo sapiens] [Reaction:1640164] ENPP7 hydrolyzes sphingomyelin [Homo sapiens] [Reaction:1861788] GBA2 hydrolyzes GlcCer (plasma membrane) [Homo sapiens] [Reaction:1606273] SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) [Homo sapiens] [Reaction:727807] SLC35A1 exchanges CMP-Neu5Ac for CMP [Homo sapiens] [BlackBoxEvent:4084990] Nuclear CMP-Neu5Ac translocates to cytosol [Homo sapiens]
releaseDate	2023-12-06
reviewed	[InstanceEdit:9851344] D'Eustachio, Peter, 2023-10-24
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9844888] R-HSA-9844860.2
summation	[Summation:9844861] Following its biosynthesis, a fraction of GalCer reaches the...
(hasEvent)	[Pathway:9840309] Glycosphingolipid biosynthesis [Homo sapiens]
(precedingEvent)	[BlackBoxEvent:9850731] Vesicles transport GSL from Golgi to plasma membrane [Homo sapiens]
[Change default viewing format]

No pathways have been reviewed or authored by ST3GAL5 transfers NeuNAc to ceramides (9844860)