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Details on Person Galactosylceramide sulfotransferase (GAL3ST1, CST) catalyzes...
| Class:Id | Summation:9844581 |
|---|---|
| _displayName | Galactosylceramide sulfotransferase (GAL3ST1, CST) catalyzes... |
| _timestamp | 2023-10-03 08:01:33 |
| created | [InstanceEdit:9844586] Stephan, Ralf, 2023-09-21 |
| modified | [InstanceEdit:9845490] Stephan, Ralf, 2023-10-03 |
| text | Galactosylceramide sulfotransferase (GAL3ST1, CST) catalyzes the transfer of sulfate from phosphoadenylylsulfate (PAPS) onto position 3 of beta-galactosyl residues in glycerolipids and sphingolipids yielding sulfogalactoceramide (sulfatide) or sulfo-LacCer (SM3), and adenosine-3',5'-bisphosphate (Honke et al., 1996, 1997). Sulfatides are abundant but not essential in the myelin sheath. GAL3ST1 deficiency leads to the arrest of spermatogenesis. It ameliorates L-selectin-dependent monocyte infiltration in renal interstitial inflammation, indicating that sulfatide is an endogenous ligand of L-selectin (reviewed by Honke, 2013). |
| (summation) | [Reaction:9844587] GAL3ST1 transfers sulfate to GalCer,LacCer [Homo sapiens] |
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No pathways have been reviewed or authored by Galactosylceramide sulfotransferase (GAL3ST1, CST) catalyzes... (9844581)
