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Details on Person Ebf2 binds target gene loci

Class:Id	Reaction:9844452
_displayName	Ebf2 binds target gene loci
_doRelease	TRUE
_timestamp	2023-11-29 18:36:48
authored	[InstanceEdit:9844988] Orlic-Milacic, Marija, 2023-09-25
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9844451] Orlic-Milacic, Marija, 2023-09-18
edited	[InstanceEdit:9855181] Orlic-Milacic, Marija, 2023-11-29
input	[DefinedSet:9854592] Ebf2, Ebf2:Blnc1 lncRNA:Hnrnpu [nucleoplasm] [Mus musculus] [DefinedSet:9854592] Ebf2, Ebf2:Blnc1 lncRNA:Hnrnpu [nucleoplasm] [Mus musculus] [DefinedSet:9854592] Ebf2, Ebf2:Blnc1 lncRNA:Hnrnpu [nucleoplasm] [Mus musculus] [DefinedSet:9854592] Ebf2, Ebf2:Blnc1 lncRNA:Hnrnpu [nucleoplasm] [Mus musculus] [DefinedSet:9854592] Ebf2, Ebf2:Blnc1 lncRNA:Hnrnpu [nucleoplasm] [Mus musculus] [DefinedSet:9854592] Ebf2, Ebf2:Blnc1 lncRNA:Hnrnpu [nucleoplasm] [Mus musculus] [DefinedSet:9854592] Ebf2, Ebf2:Blnc1 lncRNA:Hnrnpu [nucleoplasm] [Mus musculus] [DefinedSet:9854592] Ebf2, Ebf2:Blnc1 lncRNA:Hnrnpu [nucleoplasm] [Mus musculus] [CandidateSet:9854594] Ppara gene, Prdm16 gene, Ucp1 gene, (Cidea gene, Cox7a1 gene, Dio2 gene, Elovl3 gene, Ppargc1a gene) [nucleoplasm] [Mus musculus]
isChimeric	FALSE
literatureReference	[LiteratureReference:9844612] EBF2 determines and maintains brown adipocyte identity [LiteratureReference:9844609] EBF2 transcriptionally regulates brown adipogenesis via the histone reader DPF3 and the BAF chromatin remodeling complex [LiteratureReference:9844613] Ebf2 is a selective marker of brown and beige adipogenic precursor cells [LiteratureReference:9844394] ZFP423 controls EBF2 coactivator recruitment and PPARγ occupancy to determine the thermogenic plasticity of adipocytes [LiteratureReference:9844390] Zfp423 Maintains White Adipocyte Identity through Suppression of the Beige Cell Thermogenic Gene Program [LiteratureReference:9844687] BAF60a deficiency uncouples chromatin accessibility and cold sensitivity from white fat browning [LiteratureReference:9844362] A long noncoding RNA transcriptional regulatory circuit drives thermogenic adipocyte differentiation [LiteratureReference:9844400] Conserved function of the long noncoding RNA Blnc1 in brown adipocyte differentiation [LiteratureReference:9844614] EBF2 promotes the recruitment of beige adipocytes in white adipose tissue [LiteratureReference:9844565] Comparative Transcriptomic and Epigenomic Analyses Reveal New Regulators of Murine Brown Adipogenesis [LiteratureReference:9844640] Loss of TLE3 promotes the mitochondrial program in beige adipocytes and improves glucose metabolism [LiteratureReference:9844638] Id1 Promotes Obesity by Suppressing Brown Adipose Thermogenesis and White Adipose Browning
modified	[InstanceEdit:9844898] Orlic-Milacic, Marija, 2023-09-23 [InstanceEdit:9854557] Orlic-Milacic, Marija, 2023-11-28 [InstanceEdit:9854608] Orlic-Milacic, Marija, 2023-11-28 [InstanceEdit:9854775] Orlic-Milacic, Marija, 2023-11-28 [InstanceEdit:9855181] Orlic-Milacic, Marija, 2023-11-29 [InstanceEdit:9855222] Orlic-Milacic, Marija, 2023-11-29
name	Ebf2 binds target gene loci
output	[CandidateSet:9854763] Ebf2, Ebf2:Blnc1 lncRNA:Hnrnpu:Ppara gene, Prdm16 gene, Ucp1 gene, (Cidea gene, Cox7a1 gene, Dio2 gene, Elovl3 gene, Ppargc1a gene) [nucleoplasm] [Mus musculus]
releaseDate	2024-03-27
reviewed	[InstanceEdit:9854531] Chun, Tae-Hwa, 2023-11-29
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48892] Mus musculus
stableIdentifier	[StableIdentifier:9844454] R-MMU-9844452.1
structureModified	[InstanceEdit:9854608] Orlic-Milacic, Marija, 2023-11-28 [InstanceEdit:9854775] Orlic-Milacic, Marija, 2023-11-28
summation	[Summation:9844897] In mouse brown and beige adipocyte lineages Ebf2 transcripti...
(inferredFrom)	[Reaction:9844366] EBF2 binds target gene loci [Homo sapiens]
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No pathways have been reviewed or authored by Ebf2 binds target gene loci (9844452)