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Details on Person PPARG binds EBF2-bound gene loci

Class:Id	BlackBoxEvent:9844440
_displayName	PPARG binds EBF2-bound gene loci
_doRelease	TRUE
_timestamp	2024-02-27 23:47:23
authored	[InstanceEdit:9844988] Orlic-Milacic, Marija, 2023-09-25
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9844439] Orlic-Milacic, Marija, 2023-09-17
edited	[InstanceEdit:9855181] Orlic-Milacic, Marija, 2023-11-29
inferredFrom	[BlackBoxEvent:9844700] Pparg binds Ebf2-bound gene loci [Mus musculus]
input	[CandidateSet:9844661] EBF2, EBF2:Blnc1 lncRNA:HNRNPU:PPARA gene, PRDM16 gene, UCP1 gene, (CIDEA gene, PPARGC1A gene) [nucleoplasm] [Homo sapiens] [DefinedSet:9843266] PPARG:RXRA [nucleoplasm] [Homo sapiens] [DefinedSet:9843266] PPARG:RXRA [nucleoplasm] [Homo sapiens] [DefinedSet:9843266] PPARG:RXRA [nucleoplasm] [Homo sapiens] [DefinedSet:9843266] PPARG:RXRA [nucleoplasm] [Homo sapiens] [DefinedSet:9843266] PPARG:RXRA [nucleoplasm] [Homo sapiens] [CandidateSet:9844662] Brown,beige adipocyte-specific coactivators of PPARG:RXRA [nucleoplasm] [Homo sapiens] [CandidateSet:9844662] Brown,beige adipocyte-specific coactivators of PPARG:RXRA [nucleoplasm] [Homo sapiens] [CandidateSet:9844662] Brown,beige adipocyte-specific coactivators of PPARG:RXRA [nucleoplasm] [Homo sapiens] [CandidateSet:9844662] Brown,beige adipocyte-specific coactivators of PPARG:RXRA [nucleoplasm] [Homo sapiens] [CandidateSet:9844662] Brown,beige adipocyte-specific coactivators of PPARG:RXRA [nucleoplasm] [Homo sapiens] [CandidateSet:9844662] Brown,beige adipocyte-specific coactivators of PPARG:RXRA [nucleoplasm] [Homo sapiens] [CandidateSet:9844662] Brown,beige adipocyte-specific coactivators of PPARG:RXRA [nucleoplasm] [Homo sapiens] [CandidateSet:9844662] Brown,beige adipocyte-specific coactivators of PPARG:RXRA [nucleoplasm] [Homo sapiens] [CandidateSet:9844662] Brown,beige adipocyte-specific coactivators of PPARG:RXRA [nucleoplasm] [Homo sapiens] [CandidateSet:9844662] Brown,beige adipocyte-specific coactivators of PPARG:RXRA [nucleoplasm] [Homo sapiens] [CandidateSet:9844666] PPARG natural ligands [nucleoplasm] [CandidateSet:9844666] PPARG natural ligands [nucleoplasm] [CandidateSet:9844666] PPARG natural ligands [nucleoplasm] [CandidateSet:9844666] PPARG natural ligands [nucleoplasm] [CandidateSet:9844666] PPARG natural ligands [nucleoplasm] [CandidateSet:9844664] RXRA natural ligands [nucleoplasm] [CandidateSet:9844664] RXRA natural ligands [nucleoplasm] [CandidateSet:9844664] RXRA natural ligands [nucleoplasm] [CandidateSet:9844664] RXRA natural ligands [nucleoplasm] [CandidateSet:9844664] RXRA natural ligands [nucleoplasm]
internalReviewed	[InstanceEdit:9845460] Rothfels, Karen, 2023-09-29 [InstanceEdit:9845461] May, Bruce, 2023-10-01
isChimeric	FALSE
modified	[InstanceEdit:9844494] Orlic-Milacic, Marija, 2023-09-18 [InstanceEdit:9844681] Orlic-Milacic, Marija, 2023-09-21 [InstanceEdit:9844702] Orlic-Milacic, Marija, 2023-09-21 [InstanceEdit:9845471] Orlic-Milacic, Marija, 2023-10-03 [InstanceEdit:9854554] Orlic-Milacic, Marija, 2023-11-28 [InstanceEdit:9854710] Orlic-Milacic, Marija, 2023-11-28 [InstanceEdit:9855221] Orlic-Milacic, Marija, 2023-11-29 [InstanceEdit:9860956] Orlic-Milacic, Marija, 2024-02-13 [InstanceEdit:9863215] Orlic-Milacic, Marija, 2024-02-27
name	PPARG binds EBF2-bound gene loci
output	[CandidateSet:9844669] EBF2, EBF2:Blnc1 lncRNA:HNRNPU:Activated PPARG:RXRA:PPARA gene, PRDM16 gene, UCP1 gene, (CIDEA gene, PPARGC1A gene) [nucleoplasm] [Homo sapiens]
precedingEvent	[Reaction:9844366] EBF2 binds target gene loci [Homo sapiens] [Reaction:9844360] EBF2 binds Blnc1 lncRNA [Homo sapiens] [BlackBoxEvent:9844822] PPARGC1A gene expression is stimulated by EBF2 [Homo sapiens] [Reaction:9844360] EBF2 binds Blnc1 lncRNA [Homo sapiens] [BlackBoxEvent:9843832] ZNF516 and PRDM16 stimulate PPARGC1A gene expression [Homo sapiens] [Reaction:9843819] ZNF516 and PRDM16 bind PPARGC1A gene promoter [Homo sapiens]
previousReviewStatus	[ReviewStatus:9821383] three stars
releaseDate	2024-03-27
reviewed	[InstanceEdit:9854531] Chun, Tae-Hwa, 2023-11-29
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9844442] R-HSA-9844440.1
structureModified	[InstanceEdit:9844681] Orlic-Milacic, Marija, 2023-09-21 [InstanceEdit:9854710] Orlic-Milacic, Marija, 2023-11-28
summation	[Summation:9844694] Based on mouse studies, binding of EBF2 transcription factor...
(hasEvent)	[Pathway:9844594] Transcriptional regulation of brown and beige adipocyte differentiation by EBF2 [Homo sapiens]
(precedingEvent)	[BlackBoxEvent:9844415] PRDM16 gene expression is stimulated by EBF2 and PPARG and repressed by ZNF423 [Homo sapiens] [BlackBoxEvent:9844536] PPARA gene expression is stimulated by EBF2 and PPARG and repressed by ZNF423 and NuRD [Homo sapiens] [BlackBoxEvent:9844549] UCP1 gene expression is stimulated by EBF2 and PPARG and repressed by ZNF423 and NuRD [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9971891] Update Tracker - [BlackBoxEvent:9844440] PPARG binds EBF2-bound gene loci - v95:[modifyText]
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No pathways have been reviewed or authored by PPARG binds EBF2-bound gene loci (9844440)