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Details on Person EBF2 binds target gene loci
Class:Id Reaction:9844366
_displayName EBF2 binds target gene loci
_doRelease TRUE
_timestamp 2024-02-13 05:14:50
authored [InstanceEdit:9844988] Orlic-Milacic, Marija, 2023-09-25
compartment [Compartment:7660] nucleoplasm
created [InstanceEdit:9844367] Orlic-Milacic, Marija, 2023-09-15
edited [InstanceEdit:9855181] Orlic-Milacic, Marija, 2023-11-29
inferredFrom
input [CandidateSet:9844457] PPARA gene, PRDM16 gene, UCP1 gene, (CIDEA gene, COX7A1 gene, DIO2 gene, ELOVL3 gene, PPARGC1A gene) [nucleoplasm] [Homo sapiens] [DefinedSet:9844453] EBF2,EBF2:Blnc1 lncRNA:HNRNPU [nucleoplasm] [Homo sapiens] [DefinedSet:9844453] EBF2,EBF2:Blnc1 lncRNA:HNRNPU [nucleoplasm] [Homo sapiens] [DefinedSet:9844453] EBF2,EBF2:Blnc1 lncRNA:HNRNPU [nucleoplasm] [Homo sapiens] [DefinedSet:9844453] EBF2,EBF2:Blnc1 lncRNA:HNRNPU [nucleoplasm] [Homo sapiens] [DefinedSet:9844453] EBF2,EBF2:Blnc1 lncRNA:HNRNPU [nucleoplasm] [Homo sapiens] [DefinedSet:9844453] EBF2,EBF2:Blnc1 lncRNA:HNRNPU [nucleoplasm] [Homo sapiens] [DefinedSet:9844453] EBF2,EBF2:Blnc1 lncRNA:HNRNPU [nucleoplasm] [Homo sapiens] [DefinedSet:9844453] EBF2,EBF2:Blnc1 lncRNA:HNRNPU [nucleoplasm] [Homo sapiens]
internalReviewed [InstanceEdit:9845460] Rothfels, Karen, 2023-09-29 [InstanceEdit:9845461] May, Bruce, 2023-10-01
isChimeric FALSE
modified [InstanceEdit:9844420] Orlic-Milacic, Marija, 2023-09-16 [InstanceEdit:9844446] Orlic-Milacic, Marija, 2023-09-17 [InstanceEdit:9844459] Orlic-Milacic, Marija, 2023-09-18 [InstanceEdit:9844895] Orlic-Milacic, Marija, 2023-09-23 [InstanceEdit:9845468] Orlic-Milacic, Marija, 2023-10-03 [InstanceEdit:9854560] Orlic-Milacic, Marija, 2023-11-28 [InstanceEdit:9854608] Orlic-Milacic, Marija, 2023-11-28 [InstanceEdit:9855221] Orlic-Milacic, Marija, 2023-11-29 [InstanceEdit:9860956] Orlic-Milacic, Marija, 2024-02-13
name EBF2 binds target gene loci
output [CandidateSet:9844437] EBF2, EBF2:Blnc1 lncRNA:HNRNPU:PPARA gene, PRDM16 gene, UCP1 gene, (CIDEA gene, COX7A1 gene, DIO2 gene, ELOVL3 gene, PPARGC1A gene) [nucleoplasm] [Homo sapiens]
precedingEvent
previousReviewStatus [ReviewStatus:9821384] two stars
releaseDate 2024-03-27
reviewed [InstanceEdit:9854531] Chun, Tae-Hwa, 2023-11-29
reviewStatus [ReviewStatus:9821382] five stars
species [Species:48887] Homo sapiens
stableIdentifier [StableIdentifier:9844369] R-HSA-9844366.1
structureModified [InstanceEdit:9844446] Orlic-Milacic, Marija, 2023-09-17 [InstanceEdit:9844459] Orlic-Milacic, Marija, 2023-09-18 [InstanceEdit:9854608] Orlic-Milacic, Marija, 2023-11-28
summation [Summation:9844893] Based on mouse studies, EBF2 transcription factor promotes b...
(hasEvent) [Pathway:9844594] Transcriptional regulation of brown and beige adipocyte differentiation by EBF2 [Homo sapiens]
(precedingEvent) [Reaction:9844375] ZNF423 binds EBF2 at EBF2-target gene loci [Homo sapiens] [BlackBoxEvent:9844415] PRDM16 gene expression is stimulated by EBF2 and PPARG and repressed by ZNF423 [Homo sapiens] [BlackBoxEvent:9844440] PPARG binds EBF2-bound gene loci [Homo sapiens] [BlackBoxEvent:9844536] PPARA gene expression is stimulated by EBF2 and PPARG and repressed by ZNF423 and NuRD [Homo sapiens] [BlackBoxEvent:9844549] UCP1 gene expression is stimulated by EBF2 and PPARG and repressed by ZNF423 and NuRD [Homo sapiens]
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